FCM/FACS (Flow Cytometry)
(Flow cytometry analysis of NKp46 in HeLa cell line, staining at 2-5ug for 1x106cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line).)
Mouse anti-Human NKp46 Monoclonal Antibody | anti-NKp46 antibody
NKp46 antibody
Gene Names
NCR1; LY94; CD335; NKP46; NK-p46
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA
Purity
By protein-G affinity chromatography
Synonyms
NKp46, Antibody; NKp46 antibody; Natural cytotoxicity triggering receptor 1 isoform a; NCR1; LY94; NCR; NKp46 Extracellular Ig-like domain; Natural killer cell p46-related protein; hNKp46; NK-p46; NKp46; NK cell-activating receptor; Lymphocyte antigen 94 homolog; CD335 antigen; Natural cytotoxicity triggering receptor 1; anti-NKp46 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, k
Clone Number
n1D9
Purity/Purification
By protein-G affinity chromatography
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
304
Applicable Applications for anti-NKp46 antibody
FCM/FACS (Flow Cytometry), ELISA
Antigen Species
Human
Immunogen
Recombinant human Nkp46 (22-255aa) purified from E. coli
Clone Note
Anti-human Nkp46 mAb, clone n1D9, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant Nkp46.
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
FCM/FACS (Flow Cytometry)
(Flow cytometry analysis of NKp46 in HeLa cell line, staining at 2-5ug for 1x106cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line).)
FCM/FACS (Flow Cytometry)
(Flow cytometry analysis of NKp46 in HeLa cell line, staining at 2-5ug for 1x106cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line).)
FCM/FACS (Flow Cytometry)
(Flow cytometry analysis of NKp46 in PBMC, staining at 2-5ug for 1x106cells. The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG.)
FCM/FACS (Flow Cytometry)
(Flow cytometry analysis of NKp46 in PBMC, staining at 2-5ug for 1x106cells. The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG.)
Related Product Information for anti-NKp46 antibody
A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel Nk cell-specific molecule involved in human Nk cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in Nk cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
Product Categories/Family for anti-NKp46 antibody
References
Sivori, S. et al., (1997) J. Exp. Med. 186:1125-36.; Pessino, A. et al., (1998) J. Exp. Med. 188:953-60.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,409 Da
NCBI Official Full Name
natural cytotoxicity triggering receptor 1 isoform a
NCBI Official Synonym Full Names
natural cytotoxicity triggering receptor 1
NCBI Official Symbol
NCR1
NCBI Official Synonym Symbols
LY94; CD335; NKP46; NK-p46
NCBI Protein Information
natural cytotoxicity triggering receptor 1
UniProt Protein Name
Natural cytotoxicity triggering receptor 1
UniProt Gene Name
NCR1
UniProt Synonym Gene Names
LY94; NK-p46; NKp46; hNKp46
Similar Products
Product Notes
The NKp46 ncr1 (Catalog #AAA47977) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NKp46 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NKp46 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA. Researchers should empirically determine the suitability of the NKp46 ncr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NKp46, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.