IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded rat breast cancer stained with PCNA antibody using peroxidase-conjugate and AEC chromogen. Note nuclear staining of tumor cells.)
Mouse PCNA Monoclonal Antibody | anti-PCNA antibody
PCNA antibody (biotin)
Gene Names
PCNA; ATLD2
Reactivity
Human, Mouse, Insect, Yeast
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
PCNA antibody (biotin) was purified by Protein G chromatography.
Synonyms
PCNA, Antibody; PCNA antibody (biotin); Monoclonal PCNA; Anti-PCNA; PCNA; Prostate Cell Nuclear Antigen; Anti PCNA; anti-PCNA antibody
Host
Mouse
Reactivity
Human, Mouse, Insect, Yeast
Clonality
Monoclonal
Isotype
IgG2a kappa
Clone Number
PC10
Specificity
Rat
Purity/Purification
PCNA antibody (biotin) was purified by Protein G chromatography.
Form/Format
Purified from ascites fluid by protein G chromatography and supplied in 10mM PBS, pH 7.4.
Sequence Length
261
Applicable Applications for anti-PCNA antibody
WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry)
Biological Significance
Expression of proliferating cell nuclear antigen (PCNA) or cyclin or polymerase delta auxiliary protein is elevated in the nucleus during late G1 phase immediately before the onset of DNA synthesis, becoming maximal during S-phase and declining during G2 and M phases. Its level correlates directly with rates of cellular proliferation and DNA synthesis. PCNA/cyclin may act as an auxiliary protein of DNA polymerase-delta to play a fundamental role in the initiation of cell proliferation.
Cross-Reactivity
Human, mouse, insect, yeast
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Tag/Conjugate
Biotin
Immunogen
PCNA antibody (biotin) was raised in mouse using recombinant rat proliferating cell nuclear antigen protein as the immunogen.
Preparation and Storage
Store at 4 degree C.
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded rat breast cancer stained with PCNA antibody using peroxidase-conjugate and AEC chromogen. Note nuclear staining of tumor cells.)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded rat breast cancer stained with PCNA antibody using peroxidase-conjugate and AEC chromogen. Note nuclear staining of tumor cells.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human small intestine stained with PCNA antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of proliferating cell)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human small intestine stained with PCNA antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of proliferating cell)
Related Product Information for anti-PCNA antibody
Mouse monoclonal PCNA antibody (biotin)
Product Categories/Family for anti-PCNA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
36 kDa (predicted detection band MW)
NCBI Official Full Name
PCNA, partial
NCBI Official Synonym Full Names
proliferating cell nuclear antigen
NCBI Official Symbol
PCNA
NCBI Official Synonym Symbols
ATLD2
NCBI Protein Information
proliferating cell nuclear antigen
UniProt Protein Name
Proliferating cell nuclear antigen
UniProt Gene Name
PCNA
UniProt Entry Name
Q6FHF5_HUMAN
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Product Notes
The PCNA pcna (Catalog #AAA74535) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PCNA antibody (biotin) reacts with Human, Mouse, Insect, Yeast and may cross-react with other species as described in the data sheet. AAA Biotech's PCNA can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the PCNA pcna for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCNA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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