IF (Immunofluorescence)
(Immunofluorescent staining of COS7 cells transiently transfected with recombinant PDE2A protein using PDE2A antibody)
Mouse PDE2A Monoclonal Antibody | anti-PDE2A antibody
PDE2A antibody
Gene Names
PDE2A; PDE2A1; PED2A4; cGSPDE; CGS-PDE
Applications
Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay
Purity
PDE2A antibody was purified by affinity chromatography.
Synonyms
PDE2A, Antibody; PDE2A antibody; Monoclonal PDE2A; Anti-PDE2A; cGMP-stimulated cyclic nucleotide phosphodiesterase; cGMP-stimulated PDE; cGS-PDE; cyclic GMP-stimulated PDE; cyclic GMP-stimulated phosphodiesterase; pde2; pde2a; pde2a1; ; PDE2A; PDEA 2; PDEA-2; anti-PDE2A antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
4D10
Purity/Purification
PDE2A antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
941
Applicable Applications for anti-PDE2A antibody
WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Biological Significance
Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3', 5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDE1, 2, 3, 10 and 11 degrade bothcyclic nucleotides. These enzymes are involved in many signal transduction pathways.
Cross-Reactivity
Human
Immunogen
PDE2A antibody was raised in mouse using a full length recombinant protein of human PDE2A (NP_002590) produced in HEK293T cells, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescent staining of COS7 cells transiently transfected with recombinant PDE2A protein using PDE2A antibody)
IF (Immunofluorescence)
(Immunofluorescent staining of COS7 cells transiently transfected with recombinant PDE2A protein using PDE2A antibody)
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PDE2A protein (Right) or empty vector (Left) detected with PDE2A antibody)
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PDE2A protein (Right) or empty vector (Left) detected with PDE2A antibody)
FCM/FACS (Flow Cytometry)
(Flow Cytometric analysis of HEK293T cells transfected with either recombinant PDE2A protein (red) or empty vector (blue) stained using PDE2A antibody)
FCM/FACS (Flow Cytometry)
(Flow Cytometric analysis of HEK293T cells transfected with either recombinant PDE2A protein (red) or empty vector (blue) stained using PDE2A antibody)
Related Product Information for anti-PDE2A antibody
Mouse monoclonal PDE2A antibody
Product Categories/Family for anti-PDE2A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
87,235 Da
NCBI Official Full Name
cGMP-dependent 3',5'-cyclic phosphodiesterase isoform PDE2A3
NCBI Official Synonym Full Names
phosphodiesterase 2A, cGMP-stimulated
NCBI Official Symbol
PDE2A
NCBI Official Synonym Symbols
PDE2A1; PED2A4; cGSPDE; CGS-PDE
NCBI Protein Information
cGMP-dependent 3',5'-cyclic phosphodiesterase
UniProt Protein Name
cGMP-dependent 3',5'-cyclic phosphodiesterase
UniProt Gene Name
PDE2A
UniProt Synonym Gene Names
CGS-PDE; cGSPDE
UniProt Entry Name
PDE2A_HUMAN
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Product Notes
The PDE2A pde2a (Catalog #AAA106902) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PDE2A can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the PDE2A pde2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE2A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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