Application Data
(Immunoprecipitation analysis of Hela cell lysates using PEG10 antibody.)
Mouse anti-Human PEG10 Monoclonal Antibody | anti-PEG10 antibody
PEG10 Antibody
Gene Names
PEG10; EDR; HB-1; Mar2; RTL2; MEF3L; Mart2; RGAG3; SIRH1
Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Purity
Affinity purified
Synonyms
PEG10, Antibody; PEG10 Antibody; Retrotransposon-derived protein PEG10; Embryonal carcinoma differentiation-regulated protein; Mammalian retrotransposon-derived protein 2; Myelin expression factor 3-like protein 1; Paternally expressed gene 10 protein; Retrotransposon gag domain-containing protein 3; Retrotransposon-derived gag-like polyprotein; Ty3/Gypsy-like protein; anti-PEG10 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody detects endogenous levels of PEG10 and does not cross-react with related proteins.
Purity/Purification
Affinity purified
Form/Format
Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
Sequence Length
325
Applicable Applications for anti-PEG10 antibody
IP (Immunoprecipitation), WB (Western Blot)
Immunogen
Purified recombinant human PEG10 protein fragments expressed in E Coli.
Cellular Localization
Nucleus; Cytoplasm
Application Data
(Immunoprecipitation analysis of Hela cell lysates using PEG10 antibody.)
Application Data
(Immunoprecipitation analysis of Hela cell lysates using PEG10 antibody.)
Application Data
(Western blot detection of PEG10 in Hela cell lysates using PEG10 antibody (1:1000 diluted). Predicted band size:55KDa. Observed band size:55KDa, 95KDa.)
Application Data
(Western blot detection of PEG10 in Hela cell lysates using PEG10 antibody (1:1000 diluted). Predicted band size:55KDa. Observed band size:55KDa, 95KDa.)
Related Product Information for anti-PEG10 antibody
UniPort Summary Function: revents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5´-GCCTGTCTTT-3´ DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter
Entrez Summary: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a-1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of-1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010]
Entrez Summary: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a-1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of-1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010]
Product Categories/Family for anti-PEG10 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55kDa
NCBI Official Full Name
retrotransposon-derived protein PEG10 isoform 2
NCBI Official Synonym Full Names
paternally expressed 10
NCBI Official Symbol
PEG10
NCBI Official Synonym Symbols
EDR; HB-1; Mar2; RTL2; MEF3L; Mart2; RGAG3; SIRH1
NCBI Protein Information
retrotransposon-derived protein PEG10
UniProt Protein Name
Retrotransposon-derived protein PEG10
UniProt Gene Name
PEG10
UniProt Synonym Gene Names
EDR; KIAA1051; MAR2; MART2; MEF3L1; RGAG3; MEF3-like protein 1
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Product Notes
The PEG10 peg10 (Catalog #AAA111303) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PEG10 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PEG10 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the PEG10 peg10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PEG10, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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