Mouse PGE2 Monoclonal Antibody | anti-Prostaglandin E2 antibody
Prostaglandin E2; PGE2 monoclonal antibody (BG8)
Reactivity
Species Independent
Applications
ELISA
Purity
Ascites.
Synonyms
PGE2, Antibody; Prostaglandin E2; PGE2 monoclonal antibody (BG8); PGE2; Prostaglandin; anti-Prostaglandin E2 antibody
Host
Mouse
Reactivity
Species Independent
Clonality
Monoclonal
Clone Number
BG8
Purity/Purification
Ascites.
Form/Format
Liquid. Neat ascites with 0.09% sodium azide.
Applicable Applications for anti-Prostaglandin E2 antibody
ELISA
Immunogen
PGE2.
Source
Purified from mouse ascites
Preparation and Storage
Ships on blue ice
Long term storage: -20 degree C
Avoid freeze/thaw cycles.
Long term storage: -20 degree C
Avoid freeze/thaw cycles.
Related Product Information for anti-Prostaglandin E2 antibody
Prostaglandin E2 (PGE2) is an extensively studied prostaglandin owing to its predominance in inflammation, cancer, atherosclerosis, autoimmune disease, and sepsis. Oxidation of arachidonic acid by prostaglandin synthases (COX-1 and COX-2) produces prostaglandin H2 (PGH2), which is further metabolized by PGE synthases into its major product, PGE2. PGE2 mediates autocrine and paracrine signaling by binding to G-protein coupled receptors (EP1, EP2, EP3, EP4) on the cell surface, functioning to modulate phospholipase C and adenylate cyclase activity. PGE2 has been of great interest as a therapeutic target, either by modulation of its synthesis by COX inhibitors (NSAIDS) or by modulation of its receptors by downregulation or binding antagonists. PGE2 production in a variety of tissues has been shown to modulate numerous physiological processes including natriuresis in the kidney, smooth muscle elasticity in the vasculature, and the inflammatory response to damaged tissues by monocytes and macrophages.
Product Categories/Family for anti-Prostaglandin E2 antibody
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Product Notes
The Prostaglandin E2 (Catalog #AAA76988) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Prostaglandin E2; PGE2 monoclonal antibody (BG8) reacts with Species Independent and may cross-react with other species as described in the data sheet. AAA Biotech's PGE2 can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the Prostaglandin E2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGE2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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