Application Data
Mouse anti-Human Podocalyxin Monoclonal Antibody | anti-PODXL antibody
Mouse Anti-Human Podocalyxin
Gene Names
PODXL; PC; PCLP; Gp200; PCLP-1
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry
Purity
Protein G purified
Synonyms
Podocalyxin, Antibody; Mouse Anti-Human Podocalyxin; Anti-human Podocalyxin (#GB6D9C11); Podocalyxin-like protein; GCTM-2 antigen; Gp200; anti-PODXL antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
IgG1; GB6D9C11
Purity/Purification
Protein G purified
Form/Format
Lyophilized
Sequence Length
558
Applicable Applications for anti-PODXL antibody
IF (Immunofluorescence), IHC (Immunohistochemistry)
Immunogen
membrane protein fraction of isolated human glomeruli
Preparation
Monoclonal antibodies were produced with the help of BALB/c mice using a membrane protein fraction of isolated human glomeruli as the immunizing antigen.
Buffer
PBS
Preparation and Storage
The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 degree C. Frozen aliquots are stable for at least 6 months when stored at -20 degree C.
Application Data
Application Data
Application Data
Application Data
Related Product Information for anti-PODXL antibody
Podocalyxin is the major sialoprotein in the glycocalyx of glomerular podocytes. It was shown that endothelial cell membranes contain Podocalyxin. By immunoelectron microscopy Podocalyxin was localized on the luminal membrane domain of endothelial cells, in a patchy distribution. The presence of Podocalyxin was confirmed in SDS extracts of lung tissue by immunoblotting. It is concluded that (a) Podocalyxin is a widespread component of endothelial plasma membranes, (b) it is restricted to the luminal membrane domain, and (c) it is distributed unevenly on the endothelial cell surface.
References
1. Horvat et al., J Cell Biol 102:484, 1986 2. Breiteneder-Geleff et al., Am J Pathol 154:385, 1999 3. Kerosuo et al., Br J Haematol 124:809, 2004 4. Kerjaschki et al., J Cell Biol 98:1591, 1984 5. Kerjaschki et al., Am J Pathol 118:343, 1985
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58,635 Da
NCBI Official Full Name
podocalyxin isoform 1
NCBI Official Synonym Full Names
podocalyxin-like
NCBI Official Symbol
PODXL
NCBI Official Synonym Symbols
PC; PCLP; Gp200; PCLP-1
NCBI Protein Information
podocalyxin; GCTM-2 antigen; podocalyxin-like protein 1
UniProt Protein Name
Podocalyxin
UniProt Gene Name
PODXL
UniProt Synonym Gene Names
PCLP; PCLP1; PC; PCLP-1
UniProt Entry Name
PODXL_HUMAN
Similar Products
Product Notes
The PODXL podxl (Catalog #AAA79094) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human Podocalyxin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Podocalyxin can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PODXL podxl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Podocalyxin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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