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product-image-AAA314440_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of PP2A alpha/beta in paraffin-embedded Human lung cancer tissue using PP2A alpha/beta Rabbit mAb at dilution 1/50)

PP2A alpha/beta Monoclonal Antibody | anti-PP2Aalpha/beta antibody

PP2A alpha/beta Rabbit mAb

Gene Names
PPP2CA; RP-C; PP2Ac; PP2CA; PP2Calpha
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
PP2A alpha/beta, Antibody; PP2A alpha/beta Rabbit mAb; RP-C; PP2Ac; PP2CA; PP2Calpha; anti-PP2Aalpha/beta antibody
Ordering
Host
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
S04-4G4
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration
0.3mg/ml (varies by lot)
Applicable Applications for anti-PP2Aalpha/beta antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide of human PP2A alpha
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.

IHC (Immunohistochemisry)

(Immunohistochemistry of PP2A alpha/beta in paraffin-embedded Human lung cancer tissue using PP2A alpha/beta Rabbit mAb at dilution 1/50)

product-image-AAA314440_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of PP2A alpha/beta in paraffin-embedded Human lung cancer tissue using PP2A alpha/beta Rabbit mAb at dilution 1/50)

ICC (Immunocytochemistry)

(Immunocytochemistry of PP2A alpha/beta (green) in hela using PP2A alpha/beta Rabbit mAb at dilution 1/5, and DAPI(blue))

product-image-AAA314440_ICC13.jpg ICC (Immunocytochemistry) (Immunocytochemistry of PP2A alpha/beta (green) in hela using PP2A alpha/beta Rabbit mAb at dilution 1/5, and DAPI(blue))

WB (Western Blot)

(Western blot detection of PP2A alpha/beta in Rat Brain,C6,CHO-K1,Hela cell lysates using PP2A alpha/beta Rabbit mAb(1:500 diluted).Predicted band size:36kDa.Observed band size:36kDa.)

product-image-AAA314440_WB15.jpg WB (Western Blot) (Western blot detection of PP2A alpha/beta in Rat Brain,C6,CHO-K1,Hela cell lysates using PP2A alpha/beta Rabbit mAb(1:500 diluted).Predicted band size:36kDa.Observed band size:36kDa.)
Related Product Information for anti-PP2Aalpha/beta antibody
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I . Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Product Categories/Family for anti-PP2Aalpha/beta antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,594 Da
NCBI Official Full Name
serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
NCBI Official Synonym Full Names
protein phosphatase 2, catalytic subunit, alpha isozyme
NCBI Official Symbol
PPP2CA
NCBI Official Synonym Symbols
RP-C; PP2Ac; PP2CA; PP2Calpha
NCBI Protein Information
serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; replication protein C; protein phosphatase 2A catalytic subunit, alpha isoform; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; serine/threonine pr
UniProt Protein Name
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
UniProt Gene Name
PPP2CA
UniProt Synonym Gene Names
PP2A-alpha; RP-C
UniProt Entry Name
PP2AA_HUMAN

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Product Notes

The PP2Aalpha/beta ppp2ca (Catalog #AAA314440) is an Antibody produced from Recombinant Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PP2A alpha/beta Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PP2A alpha/beta can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PP2Aalpha/beta ppp2ca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PP2A alpha/beta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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