IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human liver carcinoma (A). esophagus carcinoma (B). normal spleen tissue(C). breast carcinoma (D). showing nuclear and cytoplasmic localization with DAB staining using PRAK Monoclonal Antibody.)
Mouse anti-Human PRAK Monoclonal Antibody | anti-PRAK antibody
PRAK Monoclonal Antibody
Gene Names
MAPKAPK5; MK5; MK-5; PRAK; MAPKAP-K5
Reactivity
Human
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
PRAK, Antibody; PRAK Monoclonal Antibody; MAP kinase-activated protein kinase 5; MAPKAPK5; PRAK; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein kinase; anti-PRAK antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Specificity
PRAK Monoclonal Antibody detects endogenous levels of PRAK protein.
Purity/Purification
Affinity purification
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applicable Applications for anti-PRAK antibody
ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of PRAK expressed in E coli.
Modification
Unmodified/Total
Preparation and Storage
Store at -20 degree C/1 year
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human liver carcinoma (A). esophagus carcinoma (B). normal spleen tissue(C). breast carcinoma (D). showing nuclear and cytoplasmic localization with DAB staining using PRAK Monoclonal Antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human liver carcinoma (A). esophagus carcinoma (B). normal spleen tissue(C). breast carcinoma (D). showing nuclear and cytoplasmic localization with DAB staining using PRAK Monoclonal Antibody.)
WB (Western Blot)
(Western Blot analysis using PRAK Monoclonal Antibody against truncated PRAK recombinant protein.)
WB (Western Blot)
(Western Blot analysis using PRAK Monoclonal Antibody against truncated PRAK recombinant protein.)
Related Product Information for anti-PRAK antibody
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
Product Categories/Family for anti-PRAK antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
MAP kinase-activated protein kinase 5 isoform 1
NCBI Official Synonym Full Names
mitogen-activated protein kinase-activated protein kinase 5
NCBI Official Symbol
MAPKAPK5
NCBI Official Synonym Symbols
MK5; MK-5; PRAK; MAPKAP-K5
NCBI Protein Information
MAP kinase-activated protein kinase 5; MAPKAPK-5; MAPKAP kinase 5; MAPK-activated protein kinase 5; p38-regulated/activated protein kinase
UniProt Protein Name
MAP kinase-activated protein kinase 5
UniProt Gene Name
MAPKAPK5
UniProt Synonym Gene Names
PRAK; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; PRAK
UniProt Entry Name
MAPK5_HUMAN
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Product Notes
The PRAK mapkapk5 (Catalog #AAA320203) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PRAK Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRAK can be used in a range of immunoassay formats including, but not limited to, ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PRAK mapkapk5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRAK, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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