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Application Data
Mouse PRK2 Monoclonal Antibody | anti-PRK2 antibody
PRK2 Monoclonal Antibody
Gene Names
PKN2; PAK2; PRK2; STK7; Pak-2; PRKCL2; PRO2042
Reactivity
Human, Mouse, Rat, Monkey
Applications
ELISA, Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
PRK2, Antibody; PRK2 Monoclonal Antibody; Serine/threonine-protein kinase N2; PKN2; PRK2; PRKCL2; PKN gamma; Protein kinase C-like 2; Protein-kinase C-related kinase 2; anti-PRK2 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Clonality
Monoclonal
Specificity
PRK2 Monoclonal Antibody detects endogenous levels of PRK2 protein.
Purity/Purification
Affinity purification
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applicable Applications for anti-PRK2 antibody
ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of human PRK2 expressed in E coli.
Modification
Unmodified/Total
Catalytic Activity
ATP + a protein = ADP + a phosphoprotein.
Domain
The C1 domain does not bind the diacylglycerol (DAG)
Enzyme Regulation
Activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids. Two specific sites, Thr-816 (activation loop of the kinase domain) and Thr-958 (turn motif), need to be phosphorylated for its full activation.
Function
Exhibits a preference for highly basic protein substrates.
PTM
Activated by limited proteolysis with trypsin.
|Autophosphorylated.
Belongs to the protein kinase superfamily.
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 C2 domain.
Contains 1 protein kinase domain.
Contains 3 REM (Hr1) repeats.
|Autophosphorylated.
Belongs to the protein kinase superfamily.
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 C2 domain.
Contains 1 protein kinase domain.
Contains 3 REM (Hr1) repeats.
Preparation and Storage
Store at -20 degree C/1 year
Application Data
Application Data
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of NIH/3T3 cells using PRK2 Monoclonal Antibody (blue) and negative control (red).)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of NIH/3T3 cells using PRK2 Monoclonal Antibody (blue) and negative control (red).)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded prostate tissues with DAB staining using PRK2 Monoclonal Antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded prostate tissues with DAB staining using PRK2 Monoclonal Antibody.)
WB (Western Blot)
(Western Blot analysis using PRK2 Monoclonal Antibody against PC-12 (1). Cos7 (2). K562 (3). Jurkat (4). HeLa (5). A431 (6). C6 (7). NIH/3T3 (8) and HEK293 (9) cell lysate.)
WB (Western Blot)
(Western Blot analysis using PRK2 Monoclonal Antibody against PC-12 (1). Cos7 (2). K562 (3). Jurkat (4). HeLa (5). A431 (6). C6 (7). NIH/3T3 (8) and HEK293 (9) cell lysate.)
Product Categories/Family for anti-PRK2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
984
NCBI Official Full Name
Serine/threonine-protein kinase N2
NCBI Official Synonym Full Names
protein kinase N2
NCBI Official Symbol
PKN2
NCBI Official Synonym Symbols
PAK2; PRK2; STK7; Pak-2; PRKCL2; PRO2042
NCBI Protein Information
serine/threonine-protein kinase N2; PKN gamma; protein kinase C-like 2; protein-kinase C-related kinase 2; cardiolipin-activated protein kinase Pak2
UniProt Protein Name
Serine/threonine-protein kinase N2
UniProt Gene Name
PKN2
UniProt Synonym Gene Names
PRK2; PRKCL2
UniProt Entry Name
PKN2_HUMAN
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Product Notes
The PRK2 pkn2 (Catalog #AAA320204) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PRK2 Monoclonal Antibody reacts with Human, Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's PRK2 can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PRK2 pkn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRK2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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