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product-image-AAA283109_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using Pseudouridine / 5-ribosyluracil Rabbit mAb (AAA283109) at a dilution of 1:500 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer(pH 9.0) prior to IHC staining.)

Rabbit Pseudouridine/5-ribosyluracil Monoclonal Antibody

Pseudouridine/5-ribosyluracil Rabbit mAb

Reactivity
Species independent
Applications
ELISA, Immunohistochemistry, Dot Blot
Purity
Affinity purification
Synonyms
Pseudouridine/5-ribosyluracil, Antibody; Pseudouridine/5-ribosyluracil Rabbit mAb; anti-Pseudouridine/5-ribosyluracil antibody
Ordering
Host
Rabbit
Reactivity
Species independent
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Applicable Applications for anti-Pseudouridine/5-ribosyluracil antibody
ELISA, IHC (Immunohistochemistry), DB (Dot Blot)
Immunogen
Chemical compounds corresponding to Pseudouridine/5-ribosyluracil/Y.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

IHC (Immunohistochemisry)

(Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using Pseudouridine / 5-ribosyluracil Rabbit mAb (AAA283109) at a dilution of 1:500 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer(pH 9.0) prior to IHC staining.)

product-image-AAA283109_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using Pseudouridine / 5-ribosyluracil Rabbit mAb (AAA283109) at a dilution of 1:500 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer(pH 9.0) prior to IHC staining.)

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded Rat kidney tissue using Pseudouridine / 5-ribosyluracil Rabbit mAb (AAA283109) at a dilution of 1:500 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer(pH 9.0) prior to IHC staining.)

product-image-AAA283109_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded Rat kidney tissue using Pseudouridine / 5-ribosyluracil Rabbit mAb (AAA283109) at a dilution of 1:500 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer(pH 9.0) prior to IHC staining.)

DB (Dot Blot)

(Dot-blot analysis of different sorts of chemical compounds using Pseudouridine / 5-ribosyluracil Rabbit mAb (AAA283109) at 1:1000 dilution.)

product-image-AAA283109_DB15.jpg DB (Dot Blot) (Dot-blot analysis of different sorts of chemical compounds using Pseudouridine / 5-ribosyluracil Rabbit mAb (AAA283109) at 1:1000 dilution.)
Related Product Information for anti-Pseudouridine/5-ribosyluracil antibody
Pseudouridine (psi) was among the first post-transcriptional modifications discovered and is overall one of the most abundant (1). It is present in a wide range of cellular RNAs and is highly conserved across species. psi is derived from uridine (U) via base-specific isomerization catalyzed by psi synthases. The site-specific pseudouridylation goes through either snoRNA-dependent (requires H/ACA RNP) or -independent mechanism (requires pseudouridine synthase (PUS) family enzymes)(2). It has an extra hydrogen-bond donor at its non-Watson-Crick edge. When incorporated into RNA, psi can alter RNA secondary structure by increasing base stacking, improving base pairing and rigidifying sugar-phosphate backbone5. The chemical and physical properties of RNA can be altered with the incorporation of psi, which could contribute to subsequent cellular functions.
Product Categories/Family for anti-Pseudouridine/5-ribosyluracil antibody

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Product Notes

The Pseudouridine/5-ribosyluracil (Catalog #AAA283109) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Pseudouridine/5-ribosyluracil Rabbit mAb reacts with Species independent and may cross-react with other species as described in the data sheet. AAA Biotech's Pseudouridine/5-ribosyluracil can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), DB (Dot Blot). Researchers should empirically determine the suitability of the Pseudouridine/5-ribosyluracil for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pseudouridine/5-ribosyluracil, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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