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product-image-AAA315292_IF11.jpg IF (Immunofluorescence) (Immunofluorescent analysis of SH-SY5Y cells, using Retinoblastoma Antibody.)

Retinoblastoma Recombinant Antibody | RB1 recombinant antibody

Retinoblastoma Rabbit mAb

Gene Names
RB1; RB; pRb; OSRC; pp110; p105-Rb
Reactivity
Human, Mouse
Applications
Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Affinity-chromatography
Synonyms
Retinoblastoma, Recombinant Antibody; Retinoblastoma Rabbit mAb; OSRC; RB; p105-Rb; RB1; pRb; pp110; RB1 recombinant antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Specificity
Retinoblastoma Antibody detects endogenous levels of Retinoblastoma
Purity/Purification
Affinity-chromatography
Form/Format
Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applicable Applications for RB1 recombinant antibody
IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human Retinoblastoma
Preparation and Storage
Store at +4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.

IF (Immunofluorescence)

(Immunofluorescent analysis of SH-SY5Y cells, using Retinoblastoma Antibody.)

product-image-AAA315292_IF11.jpg IF (Immunofluorescence) (Immunofluorescent analysis of SH-SY5Y cells, using Retinoblastoma Antibody.)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded human lung cancer, using Retinoblastoma Antibody.)

product-image-AAA315292_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemical analysis of paraffin-embedded human lung cancer, using Retinoblastoma Antibody.)

WB (Western Blot)

(Western blot analysis of Retinoblastoma expression in (1) Jurkat cell lysate; (2) MCF-7 cell lysate.)

product-image-AAA315292_WB15.jpg WB (Western Blot) (Western blot analysis of Retinoblastoma expression in (1) Jurkat cell lysate; (2) MCF-7 cell lysate.)
Related Product Information for RB1 recombinant antibody
The retinoblastoma tumor suppressor protein, Rb, regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle. Rb has three functionally distinct binding domains and interacts with critical regulatory proteins including the E2F family of transcription factors, c-Abl tyrosine kinase, and proteins with a conserved LXCXE motif. Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression.
Product Categories/Family for RB1 recombinant antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
106,159 Da
NCBI Official Full Name
retinoblastoma-associated protein
NCBI Official Synonym Full Names
retinoblastoma 1
NCBI Official Symbol
RB1
NCBI Official Synonym Symbols
RB; pRb; OSRC; pp110; p105-Rb
NCBI Protein Information
retinoblastoma-associated protein; retinoblastoma suspectibility protein
UniProt Protein Name
Retinoblastoma-associated protein
UniProt Gene Name
RB1
UniProt Synonym Gene Names
Rb
UniProt Entry Name
RB_HUMAN

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Product Notes

The RB1 rb1 (Catalog #AAA315292) is a Recombinant Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Retinoblastoma Rabbit mAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Retinoblastoma can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the RB1 rb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Retinoblastoma, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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