IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human small intestine stained with RRM1 Recombinant Rabbit Monoclonal (RRM1/4372R).)
Rabbit anti-Human Ribonucleotide Reductase M1/RRM1 Monoclonal Antibody | anti-RRM1 antibody
Ribonucleotide Reductase M1/RRM1 Recombinant Rabbit Monoclonal Antibody [Clone RRM1/4372R]
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
Ribonucleotide Reductase M1/RRM1, Antibody; Ribonucleotide Reductase M1/RRM1 Recombinant Rabbit Monoclonal Antibody [Clone RRM1/4372R]; Ribonucleoside diphosphate reductase large subunit; Ribonucleoside diphosphate reductase M1 chain; RR1; RRM1; RIR1; Ribonucleotide reductase M1 polypeptide; Ribonucleotide reductase R1 subunit; anti-RRM1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit/IgG
Clone Number
RRM1/4372R
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-RRM1 antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Synthetic peptide corresponding to residues within aa700-800 of human RRM1 (exact sequence is proprietary)
Cellular Localization
Cytoplasm
Positive Control
Human breast, lung or colon carcinoma tissue.
Hu-chromosome Location
11p15.4
Unigene
445705
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human small intestine stained with RRM1 Recombinant Rabbit Monoclonal (RRM1/4372R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human small intestine stained with RRM1 Recombinant Rabbit Monoclonal (RRM1/4372R).)
Related Product Information for anti-RRM1 antibody
Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.
NCBI and Uniprot Product Information
NCBI GeneID
Molecular Weight
94kDa
Similar Products
Product Notes
The RRM1 (Catalog #AAA215898) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Ribonucleotide Reductase M1/RRM1 Recombinant Rabbit Monoclonal Antibody [Clone RRM1/4372R] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ribonucleotide Reductase M1/RRM1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the RRM1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ribonucleotide Reductase M1/RRM1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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