IHC (Immunohiostchemistry)
Mouse anti-Human S100A7 Monoclonal Antibody | anti-S100A7 antibody
S100A7, Human, mAb 9F3
Gene Names
S100A7; PSOR1; S100A7c
Reactivity
Human
Applications
Western Blot, Immunofluorescence, Immunohistochemistry
Synonyms
S100A7, Antibody; S100A7, Human, mAb 9F3; anti-S100A7 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Form/Format
1 ml (100 mug/ml) 0.2 mum protein G purified antibody solution in PBS, containing 0.1% bovine serum albumin.
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml)
Sequence Length
101
Applicable Applications for anti-S100A7 antibody
WB (Western Blot), IF (Immunofluorescence), IA (Immunoassay), IHC (Immunohistochemistry)
Preparation and Storage
Should be stored at 4 degree C.
Under recommended storage conditions, product is stable for at least one year.
Under recommended storage conditions, product is stable for at least one year.
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-S100A7 antibody
Antibody 9F3 recognizes human S100A7 (Psoriasin). S100A7 is a 11.4kDa member of the S100 gene family, which are EF-hand Ca 2+-binding proteins. They are involved in a broad range of intra- and extracellular processes like regulation of calcium homeostasis, cell proliferation, differentiation, apoptosis, immune responses, antimicrobial activity, chemotaxis and inflammation. S100 proteins have a fundamental structural unit which is a highly integrated dimer, some as homodimer and others as heterodimer. S100A7 functions as a homodimer and binds two Zn2+ ions. These ions stabilize the dimer and mediate the function of S100A7 during infection. Extracellular S100A7 functions as a DAMP during infection. S100A7 limits bacterial infection through metal limitation. Furthermore, S100A7 interacts with RAGE which drives an NF-kappaB mediated proinflammatory response and recruitment of neutrophils.
S100A7 was first discovered as a protein abundantly expressed in psoriatic keratinocytes. Possibly, S100A7 adheres directly to, and reduces survival of, pathogens found on the epidermis and acts as a physical barrier. S100A7 also seems to be involved with breast cancer and squamous cell carcinoma. In vitro it was found to confer a more aggressive behavior.
S100A7 was first discovered as a protein abundantly expressed in psoriatic keratinocytes. Possibly, S100A7 adheres directly to, and reduces survival of, pathogens found on the epidermis and acts as a physical barrier. S100A7 also seems to be involved with breast cancer and squamous cell carcinoma. In vitro it was found to confer a more aggressive behavior.
Product Categories/Family for anti-S100A7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
11,471 Da
NCBI Official Full Name
S100A7
NCBI Official Synonym Full Names
S100 calcium binding protein A7
NCBI Official Symbol
S100A7
NCBI Official Synonym Symbols
PSOR1; S100A7c
NCBI Protein Information
protein S100-A7
UniProt Protein Name
Protein S100-A7
UniProt Gene Name
S100A7
UniProt Synonym Gene Names
PSOR1; S100A7C
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Product Notes
The S100A7 s100a7 (Catalog #AAA77810) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The S100A7, Human, mAb 9F3 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's S100A7 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence), IA (Immunoassay), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the S100A7 s100a7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "S100A7, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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