WB (Western Blot)
(Blot of bovine retinal extracts probed with SAG / Arrestin antibody. The antibody stains a band corresponding to retinal arrestin at about 48 kDa.)
Mouse SAG / Arrestin Monoclonal Antibody | anti-SAG antibody
Anti-SAG / Arrestin Antibody (clone S128) IHC-plus
Gene Names
SAG; RP47; S-AG
Reactivity
Mouse, Bovine, Rat, Pig, Human
Applications
Western Blot, Immunofluorescence, Immunohistochemistry
Purity
Affinity purified
Synonyms
SAG / Arrestin, Antibody; Anti-SAG / Arrestin Antibody (clone S128) IHC-plus; Mouse Monoclonal [clone S128] (IgG1,k) to Human SAG / Arrestin; Human SAG / Arrestin; 48 kDa protein; Arrestin 1; ARRESTIN; S-arrestin; S-AG; Retinal S-antigen; Rod photoreceptor arrestin; S-antigen; RP47; anti-SAG antibody
Host
Mouse
Reactivity
Mouse, Bovine, Rat, Pig, Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
S128
Specificity
Clone S128 is known to react with visual arrestin from human, bovine, mouse, pig and rat.
Purity/Purification
Affinity purified
Form/Format
PBS, 10 mM sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
405
Applicable Applications for anti-SAG antibody
WB (Western Blot), IF (Immunofluorescence), IHC (Immunohistochemistry)
Immunogen
SAG / Arrestin antibody was raised against raised against recombinant bovine arrestin-1 with the first 20 amino acids of the C-terminus truncated
Immunogen Description
raised against recombinant bovine arrestin-1 with the first 20 amino acids of the C-terminus truncated
Target Species
Human
Preparation and Storage
4 degree C or -20 degree C, Avoid repeated freezing and thawing.
WB (Western Blot)
(Blot of bovine retinal extracts probed with SAG / Arrestin antibody. The antibody stains a band corresponding to retinal arrestin at about 48 kDa.)
WB (Western Blot)
(Blot of bovine retinal extracts probed with SAG / Arrestin antibody. The antibody stains a band corresponding to retinal arrestin at about 48 kDa.)
IHC (Immunohiostchemistry)
(Confocal image of a pig retina stained with SAG / Arrestin antibody (green). Visual arrestin is most abundant in the outer segments (OS) and inner surface of the outer nuclear layer (ONL), and can be used to identify components of rod photoreceptor cells. (Cone photoreceptors have a different arrestin isotype). Other retinal layers are inner segments (IS), outer plexiform layer (OPL), inner nuclear layer (INL) and inner plexiform layer (IPL). The red stain is Fox2, an RNA binding nuclear protein related to Fox3/NeuN, which stains nuclei of horizontal neurons and some other neurons in the INL and IPL. Nuclear DNA was revealed with DAPI (blue).)
IHC (Immunohiostchemistry)
(Confocal image of a pig retina stained with SAG / Arrestin antibody (green). Visual arrestin is most abundant in the outer segments (OS) and inner surface of the outer nuclear layer (ONL), and can be used to identify components of rod photoreceptor cells. (Cone photoreceptors have a different arrestin isotype). Other retinal layers are inner segments (IS), outer plexiform layer (OPL), inner nuclear layer (INL) and inner plexiform layer (IPL). The red stain is Fox2, an RNA binding nuclear protein related to Fox3/NeuN, which stains nuclei of horizontal neurons and some other neurons in the INL and IPL. Nuclear DNA was revealed with DAPI (blue).)
IHC (Immunohistochemistry)
(Anti-SAG / Arrestin antibody IHC staining of human retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
IHC (Immunohistochemistry)
(Anti-SAG / Arrestin antibody IHC staining of human retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Related Product Information for anti-SAG antibody
SAG Antibody, 48 kDa protein Antibody, Arrestin 1 Antibody, ARRESTIN Antibody, S-arrestin Antibody, S-AG Antibody, Retinal S-antigen Antibody, Rod photoreceptor arrestin Antibody, S-antigen Antibody, RP47 Antibody Description: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,120 Da
NCBI Official Full Name
S-arrestin
NCBI Official Synonym Full Names
S-antigen; retina and pineal gland (arrestin)
NCBI Official Symbol
SAG
NCBI Official Synonym Symbols
RP47; S-AG
NCBI Protein Information
S-arrestin
UniProt Protein Name
S-arrestin
UniProt Gene Name
SAG
UniProt Synonym Gene Names
S-AG
UniProt Entry Name
ARRS_HUMAN
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Product Notes
The SAG sag (Catalog #AAA52580) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-SAG / Arrestin Antibody (clone S128) IHC-plus reacts with Mouse, Bovine, Rat, Pig, Human and may cross-react with other species as described in the data sheet. AAA Biotech's SAG / Arrestin can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the SAG sag for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SAG / Arrestin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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