anti-Human Selicrelumab Monoclonal Antibody | anti-CD40 antibody
Research Grade Selicrelumab
Gene Names
CD40; p50; Bp50; CDW40; TNFRSF5
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Selicrelumab, Antibody; Research Grade Selicrelumab; CP-870; 893; RG-7876; RO-7009789; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; TNFRSF5; CDw40; CD40; anti-CD40 antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. 0.01m PBS, pH7.4
Concentration
2.57mg/ml (varies by lot)
Target
Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40
Expression System
Mammalian Cells
Host Species
Human
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Product Categories/Family for anti-CD40 antibody
References
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans, PMID: 21436454
Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer, PMID: 34112709
Co-Stimulatory versus Cell Death Aspects of Agonistic CD40 Monoclonal Antibody Selicrelumab in Chronic Lymphocytic Leukemia, PMID: 34205588
Immunotherapy of cancer in 2012, PMID: 22576456
Agonistic CD40 Antibodies in Cancer Treatment, PMID: 33804039
Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer, PMID: 34112709
Co-Stimulatory versus Cell Death Aspects of Agonistic CD40 Monoclonal Antibody Selicrelumab in Chronic Lymphocytic Leukemia, PMID: 34205588
Immunotherapy of cancer in 2012, PMID: 22576456
Agonistic CD40 Antibodies in Cancer Treatment, PMID: 33804039
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 5 isoform 1
NCBI Official Synonym Full Names
CD40 molecule, TNF receptor superfamily member 5
NCBI Official Symbol
CD40
NCBI Official Synonym Symbols
p50; Bp50; CDW40; TNFRSF5
NCBI Protein Information
tumor necrosis factor receptor superfamily member 5; CD40L receptor; CD40 type II isoform; B cell-associated molecule; B cell surface antigen CD40; B-cell surface antigen CD40; CD40 antigen (TNF receptor superfamily member 5); tumor necrosis factor recept
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 5
UniProt Gene Name
CD40
UniProt Synonym Gene Names
TNFRSF5
UniProt Entry Name
TNR5_HUMAN
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Product Notes
The CD40 cd40 (Catalog #AAA120064) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Selicrelumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Selicrelumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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