Mouse anti-Human SerpinA7 Monoclonal Antibody | anti-SerpinA7 antibody
Mouse anti Human SerpinA7 Monoclonal Antibody
Gene Names
SERPINA7; TBG; TBGQTL
Reactivity
Human
Applications
ELISA
Synonyms
SerpinA7, Antibody; Mouse anti Human SerpinA7 Monoclonal Antibody; anti-SerpinA7 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Applicable Applications for anti-SerpinA7 antibody
ELISA
Immunogen
Recombinant Human SerpinA7 protein
Buffer
PBS with 0.05% sodium azide, 30% glycerol and 5% trehalose
Produce
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Serpin A7. The IgG fraction of the cell culture supertanant was purified by protein A affinity chromatography.
Preparation and Storage
Store at -20°C, Avoid freeze/thaw cycles
Related Product Information for anti-SerpinA7 antibody
Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein which belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG binds thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 and T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
SERPINA7, partial
NCBI Official Synonym Full Names
serpin family A member 7
NCBI Official Symbol
SERPINA7
NCBI Official Synonym Symbols
TBG; TBGQTL
NCBI Protein Information
thyroxine-binding globulin
UniProt Protein Name
Thyroxine-binding globulin
UniProt Gene Name
SERPINA7
UniProt Synonym Gene Names
TBG
UniProt Entry Name
THBG_HUMAN
Similar Products
Product Notes
The SerpinA7 serpina7 (Catalog #AAA173443) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse anti Human SerpinA7 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SerpinA7 can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the SerpinA7 serpina7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SerpinA7, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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