<
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Raji cells with SHIP antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody)
Rabbit anti-Human SHIP Monoclonal Antibody | anti-SHIP antibody
SHIP Antibody
Gene Names
INPP5D; SHIP; SHIP1; SHIP-1; hp51CN; SIP-145
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunoprecipitation, Immunohistochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
SHIP, Antibody; SHIP Antibody; Inositol polyphosphate 5 phosphatase of 145kDa antibody; 4 antibody; 5-trisphosphate 5-phosphatase 1 antibody; hp51CN antibody; Inositol polyphosphate 5 phosphatase 145kDa antibody; Inositol polyphosphate 5 phosphatase antibody; Inositol polyphosphate-5-phosphatase of 145 kDa antibody; INPP5D antibody; MGC104855 antibody; MGC142140 antibody; MGC142142 antibody; p150Ship antibody; Phosphatidylinositol 3; 4; 5 trisphosphate 5 phosphatase 1 antibody; Phosphatidylinositol-3 antibody; SH2 containing inositol phosphatase isoform b antibody; SH2 domain containing inositol 5' phosphatase 1 antibody; SH2 domain containing inositol phosphatase 1 antibody; SH2 domain-containing inositol phosphatase 1 antibody; SH2 domain-containing inositol-5''-phosphatase 1 antibody; SHIP-1 antibody; SHIP1 antibody; SHIP1_HUMAN antibody; Signaling inositol polyphosphate 5 phosphatase SIP 145 antibody; SIP-145 antibody; SIP145 antibody; anti-SHIP antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Clone Number
SY11-08
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-SHIP antibody
FCM/FACS (Flow Cytometry), IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Raji cells with SHIP antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Raji cells with SHIP antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-SHIP antibody. Counter stained with hematoxylin.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-SHIP antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-SHIP antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-SHIP antibody. Counter stained with hematoxylin.)
WB (Western Blot)
(Western blot analysis of SHIP on different lysates using anti-SHIP antibody at 1/1, 000 dilution. Positive control: Lane 1: Daudi Lane 2: THP-1)
WB (Western Blot)
(Western blot analysis of SHIP on different lysates using anti-SHIP antibody at 1/1, 000 dilution. Positive control: Lane 1: Daudi Lane 2: THP-1)
Related Product Information for anti-SHIP antibody
The major translational product of the v-Fms oncogene, originally isolated from the McDonough strain of feline sarcoma virus, has been identified as a glycoprotein with intrinsic tyrosine kinase activity. The v-Fms human cellular homolog, c-Fms, has been molecularly cloned and mapped to band q34 on chromosome 5, and identified as the receptor for hematopoietic ligand, CSF-1. Ligand-induced activation of the intrinsic CSF-1R protein tyrosine kinase triggers its interaction with cytoplasmic effector molecules. One such effector molecule, SHIP-1 p145 (SH2-containing-inositol phosphatase), associates with activated Fms. SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3, 4, 5-triphosphate and inositol 1, 3, 4, 5-tetrakisphosphate polyphosphate 5-phosphatase activity. Evidence suggests that SHIP-1 may modulate Ras signaling in addition to inositol signaling pathways.
Product Categories/Family for anti-SHIP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
133,292 Da
NCBI Official Full Name
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform a
NCBI Official Synonym Full Names
inositol polyphosphate-5-phosphatase, 145kDa
NCBI Official Symbol
INPP5D
NCBI Official Synonym Symbols
SHIP; SHIP1; SHIP-1; hp51CN; SIP-145
NCBI Protein Information
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; p150Ship; SH2 domain-containing inositol phosphatase 1; SH2 containing inositol phosphatase, isoform b; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol-5'-phosphatas
UniProt Protein Name
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
UniProt Gene Name
INPP5D
UniProt Synonym Gene Names
SHIP; SHIP1; SIP-145; SH2 domain-containing inositol phosphatase 1; SHIP-1; hp51CN
UniProt Entry Name
SHIP1_HUMAN
Similar Products
Product Notes
The SHIP inpp5d (Catalog #AAA312180) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SHIP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SHIP can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SHIP inpp5d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SHIP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.