Rabbit Spectrin Alpha 1 Monoclonal Antibody | anti-SPTA1 antibody

Spectrin Alpha 1 (Erythrocyte Marker)

Cat. Num. AAA214820

• Gene Names: SPTA1; EL2; HPP; HS3; SPH3; SPTA
• Reactivity: Human. Others not known.
• Applications: Immunohistochemistry, ELISA
• Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: Spectrin Alpha 1, Antibody; Spectrin Alpha 1 (Erythrocyte Marker); Alpha I spectrin; Elliptocytosis 2 (EL2); Erythrocyte alpha spectrin; Erythroid alpha-spectrin; HPP; HS3; Spectrin alpha erythrocytic 1; SPH3; SPTA1; anti-SPTA1 antibody

• Host: Rabbit
• Reactivity: Human. Others not known.
• Clonality: Monoclonal
• Isotype: IgG
• Clone Number: SPTA1/2939R
• Specificity: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous alpha and beta chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin alpha I and spectrin beta I are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta II (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 2,416

• Applicable Applications for anti-SPTA1 antibody: IHC (Immunohistochemistry), ELISA
• Immunogen: Recombinant fragment of human SPTA (around aa356-475) (exact sequence is proprietary)
• Positive Control: Jurkat Cells. Placenta or Tonsil.
• Cellular Localization: Cytoplasmic and Cell Surface
• Chromosome Location: 1q23.1
• Preparation and Storage: Antibody with azide - store at 2 to 8 degree C.; Antibody without azide - store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohistochemisry)

(Formalin-fixed, paraffin-embedded human Pancreas stained with Spectrin alpha 1 Rabbit Recombinant Monoclonal Antibody (SPTA1/2939R).)

SDS-PAGE

(SDS-PAGE Analysis Purified Spectrin alpha 1 Rabbit Recombinant Monoclonal (SPTA1/2939R). Confirmation of Purity and Integrity of Antibody.)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Pancreas stained with Spectrin alpha 1 Rabbit Recombinant Monoclonal Antibody (SPTA1/2939R).)

Related Product Information for anti-SPTA1 antibody

Recombinant Rabbit Monoclonal Antibody

References

Speicher, D.W. 1986. J. Cell. Biochem. 30: 245-258.

NCBI and Uniprot Product Information

• NCBI GI #: 115298659
• NCBI GeneID: 6708
• NCBI Accession #: NP_003117.2
• NCBI GenBank Nucleotide #: NM_003126.3
• UniProt Accession #: P02549; Q15514; Q5VYL1; Q5VYL2; Q6LDY5
• Molecular Weight: 240kDa
• NCBI Official Full Name: spectrin alpha chain, erythrocytic 1
• NCBI Official Synonym Full Names: spectrin alpha, erythrocytic 1
• NCBI Official Symbol: SPTA1
• NCBI Official Synonym Symbols: EL2; HPP; HS3; SPH3; SPTA
• NCBI Protein Information: spectrin alpha chain, erythrocytic 1
• UniProt Protein Name: Spectrin alpha chain, erythrocytic 1
• UniProt Gene Name: SPTA1
• UniProt Synonym Gene Names: SPTA