Mouse anti-Human TAF15 Monoclonal Antibody | anti-TAF15 antibody

Mouse monoclonal antibody Anti-Human TAF15

Cat. Num. AAA36351

• Gene Names: TAF15; Npl3; RBP56; TAF2N; TAFII68
• Reactivity: Human
• Applications: Immunocytochemistry, Dot Blot
• Synonyms: TAF15, Antibody; Mouse monoclonal antibody Anti-Human TAF15; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa; TAFII68; RBP56; TAF2N; hTAFII68; anti-TAF15 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: TAF15B11A6
• Concentration: 100 ug/ml (1.0 ml) (varies by lot)
• Sequence Length: 2188

• Applicable Applications for anti-TAF15 antibody: ICC (Immunocytochemistry), DB (Dot Blot)
• Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
• Sterility: Filtered through a 0.22 um membrane.

ICC (Immunocytochemistry)

(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-TAF15 mAb. [Lot No.TAF15B11A6-2])

Quality Control #2

(Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)

Quality Control

(Western blot analysis of immunized recombinant protein, using anti-TAF15 monoclonal antibody.)

Related Product Information for anti-TAF15 antibody

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified. [NCBI Entrez Gene Summary]

NCBI and Uniprot Product Information

• NCBI GI #: 28279784
• NCBI GeneID: 8148
• Molecular Weight: 61,558 Da
• NCBI Official Full Name: Homo sapiens TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa, mRNA
• NCBI Official Synonym Full Names: TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
• NCBI Official Symbol: TAF15
• NCBI Official Synonym Symbols: Npl3; RBP56; TAF2N; TAFII68
• NCBI Protein Information: TATA-binding protein-associated factor 2N; RBP56/CSMF fusion; TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56); TATA box-binding protein-associated factor 2N (RNA-binding protein 56); TBP-associated factor 15
• UniProt Protein Name: TATA-binding protein-associated factor 2N
• UniProt Gene Name: TAF15
• UniProt Entry Name: RBP56_HUMAN