SDS-PAGE
(SDS-PAGE Analysis Purified Tal1 Mouse Monoclonal Antibody (BTL73). Confirmation of Integrity and Purity of Antibody.)
Mouse anti-Human Tal1 Monoclonal Antibody | anti-TAL1 antibody
Tal1
Gene Names
TAL1; SCL; TCL5; tal-1; bHLHa17
Reactivity
Human
Applications
Western Blot, ELISA
Synonyms
Tal1, Antibody; Tal1; bHLHa17; Class A basic helix-loop-helix protein 17; OTTHUMP00000009563; OTTHUMP00000009564; SCL; STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR; Stem cell protein; T cell acute lymphocytic leukemia 1; T cell acute lymphocytic leukemia 1 protein; T cell leukemia/lymphoma 5 protein; T-cell acute lymphocytic leukemia protein 1; T-cell leukemia/lymphoma protein 5; Tal 1 product; TAL 1 protein; TAL bHLH transcription factor 1 erythroid differentiation factor; TAL-1; anti-TAL1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
BTL73
Specificity
Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.
Form/Format
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Sequence Length
331
Applicable Applications for anti-TAL1 antibody
WB (Western Blot), ELISA
Positive Control
A549 xenograft.
Immunogen
Recombinant human full-length TAL1 protein
Cellular Localization
Nucleus
Research Area
Cardiovascular, Developmental Biology, Nuclear Marker, Transcription Factors
Preparation and Storage
Store at -20°C. Non-Hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified Tal1 Mouse Monoclonal Antibody (BTL73). Confirmation of Integrity and Purity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified Tal1 Mouse Monoclonal Antibody (BTL73). Confirmation of Integrity and Purity of Antibody.)
References
Chetty, R., et al. 1996. J. Pathol. 178: 311-315.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
T-cell acute lymphocytic leukemia protein 1 isoform 1
NCBI Official Synonym Full Names
TAL bHLH transcription factor 1, erythroid differentiation factor
NCBI Official Symbol
TAL1
NCBI Official Synonym Symbols
SCL; TCL5; tal-1; bHLHa17
NCBI Protein Information
T-cell acute lymphocytic leukemia protein 1
UniProt Protein Name
T-cell acute lymphocytic leukemia protein 1
UniProt Gene Name
TAL1
UniProt Synonym Gene Names
BHLHA17; SCL; TCL5; TAL-1; bHLHa17
UniProt Entry Name
TAL1_HUMAN
Similar Products
Product Notes
The TAL1 tal1 (Catalog #AAA215213) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Tal1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Tal1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TAL1 tal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tal1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.