IF (Immunofluorescence)
(Confocal immunofluorescent analysis of TBB1 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).)
Mouse anti-Human, mouse TBB1 Monoclonal Antibody | anti-TUBB1 antibody
TBB1 Antibody
Reactivity
Human, mouse
Applications
Immunofluorescence, Immunohistochemistry, ELISA, Western Blot
Purity
Purified Mouse Monoclonal Antibody (Mab)
Synonyms
TBB1, Antibody; TBB1 Antibody; Tubulin beta-1 chain; TUBB1; anti-TUBB1 antibody
Host
Mouse
Reactivity
Human, mouse
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
86CT4.4.4
Specificity
This monoclonal antibody is generated from mice immunized with a recombinant protein human TBB1.
Purity/Purification
Purified Mouse Monoclonal Antibody (Mab)
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Length
451
Applicable Applications for anti-TUBB1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Recombinant Protein
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of TBB1 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of TBB1 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human brain reacted with TBB1 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human brain reacted with TBB1 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of anti-TBB1 Antibody in mouse brain tissue, Y79, CEM and 293 lysates (35ug/lane). TBB1 (arrow) was detected using the purified Mab.(1ug/ml))
WB (Western Blot)
(Western blot analysis of anti-TBB1 Antibody in mouse brain tissue, Y79, CEM and 293 lysates (35ug/lane). TBB1 (arrow) was detected using the purified Mab.(1ug/ml))
Related Product Information for anti-TUBB1 antibody
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
Product Categories/Family for anti-TUBB1 antibody
References
Study of 18 functional hemostatic polymorphisms in mucocutaneous bleeding disorders. Antón AI, et al. Ann Hematol, 2010 Nov. PMID 20532885.
Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of beta-tubulin at Cys 12 and suppression of microtubule dynamics. Xu W, et al. Mol Cancer Ther, 2009 Dec. PMID 19996274.
Genotype-phenotype relationship for six common polymorphisms in genes affecting platelet function from 286 healthy subjects and 160 patients with mucocutaneous bleeding of unknown cause. Martínez C, et al. Br J Haematol, 2009 Jun. PMID 19388931.
TUBB1 Q43P polymorphism does not protect against acute coronary syndrome and premature myocardial infarction. Navarro-Núñez L, et al. Thromb Haemost, 2008 Dec. PMID 19132255.
Roles of beta-tubulin residues Ala428 and Thr429 in microtubule formation in vivo. Joe PA, et al. J Biol Chem, 2009 Feb 13. PMID 19074767.
Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of beta-tubulin at Cys 12 and suppression of microtubule dynamics. Xu W, et al. Mol Cancer Ther, 2009 Dec. PMID 19996274.
Genotype-phenotype relationship for six common polymorphisms in genes affecting platelet function from 286 healthy subjects and 160 patients with mucocutaneous bleeding of unknown cause. Martínez C, et al. Br J Haematol, 2009 Jun. PMID 19388931.
TUBB1 Q43P polymorphism does not protect against acute coronary syndrome and premature myocardial infarction. Navarro-Núñez L, et al. Thromb Haemost, 2008 Dec. PMID 19132255.
Roles of beta-tubulin residues Ala428 and Thr429 in microtubule formation in vivo. Joe PA, et al. J Biol Chem, 2009 Feb 13. PMID 19074767.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50327
NCBI Official Full Name
tubulin beta-1 chain
NCBI Official Synonym Full Names
tubulin, beta 1 class VI
NCBI Official Symbol
TUBB1
NCBI Protein Information
tubulin beta-1 chain
UniProt Protein Name
Tubulin beta-1 chain
UniProt Gene Name
TUBB1
UniProt Entry Name
TBB1_HUMAN
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Product Notes
The TUBB1 tubb1 (Catalog #AAA283564) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TBB1 Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TBB1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the TUBB1 tubb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TBB1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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