Rabbit TBR1 Monoclonal Antibody | anti-TBR1 antibody
TBR1
Gene Names
TBR1; TBR-1; TES-56
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
Purity
Protein A affinity purified
Synonyms
TBR1, Antibody; TBR1; T-box brain protein 1; TES-56; anti-TBR1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
JF10-00
Purity/Purification
Protein A affinity purified
Form/Format
1*TBS (pH 7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide
Sequence Length
682
Applicable Applications for anti-TBR1 antibody
IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot)
Product Type
Recombinant Protein
Conjugation
AF488
Subcellular Location
Nucleus
Preparation and Storage
Store at +4°C after thawing.
Aliquot and store at-20°C or -80°C.
Avoid repeated freeze/thaw cycles.
Aliquot and store at-20°C or -80°C.
Avoid repeated freeze/thaw cycles.
Related Product Information for anti-TBR1 antibody
A novel murine and human gene, TBR-1, encodes a putative transcription factor related to the Brachyrury (T) gene that is expressed only in postmitotic cells. T-brain-1 (TBR-1) mRNA is largely restricted to the cerebral cortex, where, during embryogenesis, it defines different regions that give rise to the palecortex, limbic cortex and neocortex. TBR-1, Pax-6 and Emx-1 are expressed in the mouse and chicken pallium. The pallio-subpallial boundary lies at the interface between the TBR-1 and Dlx-2 expression domains. Chicken genes homolgous to these mouse genes are expressed in topologically comparable patterns during development, suggesting that mouse and chicken may have similar histogenetic specification processes and field homologies. CASK/LIN-2, a membrane-associated guanylate kinase, is required for EGFR localization and signaling, In adult rat brain, CASK is concentrated at neuronal synapses and binds to the cell-surface proteins. CASK can interact with TBR-1, which is involved in forebrain development. CASK enters into the nucleus and binds to a specific DNA sequence (the T-element) in a complex with TBR-1. Thus, CASK acts as a coactivator of TBR-1 to induce transcription of T-element containing genes, including reelin.Immunogen: Synthetic peptide within Human TBR1 aa 30-75 / 682.Positive control: Mouse brain tissue lysates, rat brain tissue, mouse brain tissue, SH-SY5Y, rat hippocampus tissue, mouse hippocampus tissue.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted band size: 74 kDa
NCBI Official Full Name
T-box brain protein 1
NCBI Official Synonym Full Names
T-box, brain 1
NCBI Official Symbol
TBR1
NCBI Official Synonym Symbols
TBR-1; TES-56
NCBI Protein Information
T-box brain protein 1
UniProt Protein Name
T-box brain protein 1
UniProt Gene Name
TBR1
UniProt Synonym Gene Names
T-brain-1; TBR-1
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Product Notes
The TBR1 tbr1 (Catalog #AAA268414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TBR1 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TBR1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TBR1 tbr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TBR1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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