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product-image-AAA214841_SDS_PAGE11.jpg SDS-PAGE (SDS-PAGE Analysis Purified TCL1 Recombinant Rabbit Monoclonal Antibody (TCL1/2747R). Confirmation of Purity and Integrity of Antibody.)

Rabbit TCL1 Monoclonal Antibody | anti-TCL1 antibody

TCL1 (T-Cell Marker)

Gene Names
TCL1A; TCL1
Reactivity
Human. Others not known.
Applications
Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
TCL1, Antibody; TCL1 (T-Cell Marker); TCL1A; Lymphoma/leukemia, T-cell; Oncogene TCL1; P14 TCL1; T cell leukemia 1; T cell lymphoma 1; T cell lymphoma 1A; T-cell leukemia/lymphoma 1A; TCL1; anti-TCL1 antibody
Ordering
Host
Rabbit
Reactivity
Human. Others not known.
Clonality
Monoclonal
Isotype
IgG
Clone Number
TCL1/2747R
Specificity
T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
114
Applicable Applications for anti-TCL1 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant human TCL1 protein fragment (around aa 2-109) (exact sequence is proprietary)
Positive Control
Ramos or Raji Cells. Tonsil or T-cell Lymphoma.
Cellular Localization
Nuclear and Cytoplasmic
Chromosome Location
14q32.13
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified TCL1 Recombinant Rabbit Monoclonal Antibody (TCL1/2747R). Confirmation of Purity and Integrity of Antibody.)

product-image-AAA214841_SDS_PAGE11.jpg SDS-PAGE (SDS-PAGE Analysis Purified TCL1 Recombinant Rabbit Monoclonal Antibody (TCL1/2747R). Confirmation of Purity and Integrity of Antibody.)

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human Tonsil stained with TCL1 Recombinant Rabbit Monoclonal Antibody (TCL1/2747R).)

product-image-AAA214841_IHC13.jpg IHC (Immunohiostchemistry) (Formalin-fixed, paraffin-embedded human Tonsil stained with TCL1 Recombinant Rabbit Monoclonal Antibody (TCL1/2747R).)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Tonsil stained with TCL1 Recombinant Rabbit Monoclonal Antibody (TCL1/2747R).)

product-image-AAA214841_IHC15.jpg IHC (Immunohistochemistry) (Formalin-fixed, paraffin-embedded human Tonsil stained with TCL1 Recombinant Rabbit Monoclonal Antibody (TCL1/2747R).)
Related Product Information for anti-TCL1 antibody
Recombinant Rabbit Monoclonal Antibody
References
Roos J, et al. Pathobiology. 2001; 69:59-66.; Narducci MG, et al. Cancer Res. 2000; 60:2095-100.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14kDa
NCBI Official Full Name
T-cell leukemia/lymphoma protein 1A
NCBI Official Synonym Full Names
T cell leukemia/lymphoma 1A
NCBI Official Symbol
TCL1A
NCBI Official Synonym Symbols
TCL1
NCBI Protein Information
T-cell leukemia/lymphoma protein 1A
UniProt Protein Name
T-cell leukemia/lymphoma protein 1A
UniProt Gene Name
TCL1A
UniProt Synonym Gene Names
TCL1; Oncogene TCL1

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Product Notes

The TCL1 tcl1a (Catalog #AAA214841) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TCL1 (T-Cell Marker) reacts with Human. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's TCL1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TCL1 tcl1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TCL1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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