Tefibazumab Monoclonal Antibody | anti-clfA antibody
Research Grade Tefibazumab
Reactivity
Staphylococcus aureus
Purity
>95% by SDS-PAGE; Protein A or G purified from cell culture supernatant.
Synonyms
Tefibazumab, Antibody; Research Grade Tefibazumab; Aurexis; clumping factor A; ClfA; anti-clfA antibody
Reactivity
Staphylococcus aureus
Clonality
Monoclonal
Isotype
IgG1-kappa
Purity/Purification
>95% by SDS-PAGE; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid; 0.01M PBS, pH7.4
Concentration
3.62 mg/ml (varies by lot)
Expression System
XtenCHO
Host Species
Humanized
CAS
521079-87-8
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4°C for short term (1-2 weeks).
Store at -20°C for 12 months.
Store at -80°C for long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at -20°C for 12 months.
Store at -80°C for long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Product Categories/Family for anti-clfA antibody
References
Open-label, dose escalation study of the safety and pharmacokinetic profile of tefibazumab in healthy volunteers, PMID: 15728889
Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia, PMID: 16870768
Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody, PMID: 27789272
Phase I dose escalation study to evaluate the safety and pharmacokinetic profile of tefibazumab in subjects with end-stage renal disease requiring hemodialysis, PMID: 17005843
A humanized monoclonal antibody targeting Staphylococcus aureus, PMID: 15576200
Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia, PMID: 16870768
Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody, PMID: 27789272
Phase I dose escalation study to evaluate the safety and pharmacokinetic profile of tefibazumab in subjects with end-stage renal disease requiring hemodialysis, PMID: 17005843
A humanized monoclonal antibody targeting Staphylococcus aureus, PMID: 15576200
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
clumping factor A
UniProt Protein Name
Clumping factor A
UniProt Gene Name
clfA
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Product Notes
The Tefibazumab clfa (Catalog #AAA120157) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Tefibazumab reacts with Staphylococcus aureus and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Tefibazumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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