IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffinembedded Rat brain tissue using TGFB1 Monoclonal Antibody at dilution of 1:200.)
Mouse anti-Mouse, Rat TGFbeta1 Monoclonal Antibody | anti-TGFbeta1 antibody
TGFbeta1 Monoclonal Antibody
Gene Names
TGFB1; CED; LAP; DPD1; TGFB; TGFbeta
Reactivity
Mouse, Rat
Applications
Immunohistochemistry
Purity
Protein A Purification
Synonyms
TGFbeta1, Antibody; TGFbeta1 Monoclonal Antibody; TGFB1; anti-TGFbeta1 antibody
Host
Mouse
Reactivity
Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
5D2
Purity/Purification
Protein A Purification
Sequence Length
390
Applicable Applications for anti-TGFbeta1 antibody
IHC (Immunohistochemistry)
Immunogen
Synthetic Peptide of TGFbeta1
Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffinembedded Rat brain tissue using TGFB1 Monoclonal Antibody at dilution of 1:200.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffinembedded Rat brain tissue using TGFB1 Monoclonal Antibody at dilution of 1:200.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffinembedded Mouse liver tissue using TGFB1 Monoclonal Antibody at dilution of 1:200.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffinembedded Mouse liver tissue using TGFB1 Monoclonal Antibody at dilution of 1:200.)
Related Product Information for anti-TGFbeta1 antibody
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,341 Da
NCBI Official Full Name
transforming growth factor beta-1 preproprotein
NCBI Official Synonym Full Names
transforming growth factor beta 1
NCBI Official Symbol
TGFB1
NCBI Official Synonym Symbols
CED; LAP; DPD1; TGFB; TGFbeta
NCBI Protein Information
transforming growth factor beta-1
UniProt Protein Name
Transforming growth factor beta-1
UniProt Gene Name
TGFB1
UniProt Synonym Gene Names
TGFB; TGF-beta-1; LAP
Similar Products
Product Notes
The TGFbeta1 tgfb1 (Catalog #AAA173686) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TGFbeta1 Monoclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TGFbeta1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TGFbeta1 tgfb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGFbeta1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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