SDS-PAGE
(SDS-PAGE Analysis Purified TSH beta Mouse Monoclonal Antibody (TSHb/1317). Confirmation of Purity and Integrity of Antibody.)
Mouse anti-Human Thyroid Stimulating Hormone, beta (TSH beta) Monoclonal Antibody | anti-TSHB antibody
Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker)
Gene Names
TSHB; TSH-B; TSH-BETA
Reactivity
Human
Applications
Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA at 1.0mg/ml
Synonyms
Thyroid Stimulating Hormone, beta (TSH beta), Antibody; Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker); CHNG4; Thyroid stimulating hormone beta subunit; Thyroid stimulating hormone; beta precursor; Thyrotropin beta subunit; TSHB; anti-TSHB antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
TSHb/1317
Specificity
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA at 1.0mg/ml
Form/Format
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Sequence Length
138
Applicable Applications for anti-TSHB antibody
IHC (Immunohistochemistry)
Positive Control
Normal pituitary or its tumor.
Immunogen
Recombinant human TSH beta fragment
Cellular Localization
Cytoplasmic
Hu-chromosome Location
1p13
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified TSH beta Mouse Monoclonal Antibody (TSHb/1317). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified TSH beta Mouse Monoclonal Antibody (TSHb/1317). Confirmation of Purity and Integrity of Antibody.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Pituitary stained with TSH beta Mouse Monoclonal Antibody (TSHb/1317).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Pituitary stained with TSH beta Mouse Monoclonal Antibody (TSHb/1317).)
References
Immunohistochemical studies of human FSH producing pituitary adenomas. Osamura, R.Y., Watanabe, K. Virchows Archiv. A, Pathological anatomy and histopathology. (1988)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16kDa
NCBI Official Full Name
thyrotropin subunit beta isoform 1
NCBI Official Synonym Full Names
thyroid stimulating hormone subunit beta
NCBI Official Symbol
TSHB
NCBI Official Synonym Symbols
TSH-B; TSH-BETA
NCBI Protein Information
thyrotropin subunit beta
UniProt Protein Name
Thyrotropin subunit beta
UniProt Gene Name
TSHB
UniProt Synonym Gene Names
TSH-B; TSH-beta
UniProt Entry Name
TSHB_HUMAN
Customer Reviews
Loading reviews...
Share Your Experience
Similar Products
Product Notes
The TSHB tshb (Catalog #AAA215239) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Thyroid Stimulating Hormone, beta (TSH beta) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TSHB tshb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thyroid Stimulating Hormone, beta (TSH beta), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.