SDS-PAGE
(SDS-PAGE Analysis Purified TIMP2 Rabbit Recombinant Monoclonal Antibody (TIMP2/2488R). Confirmation of Purity and Integrity of Antibody.)
Rabbit TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody | anti-TIMP2 antibody
TIMP2 (Tissue Inhibitor of Metalloproteinase 2)
Gene Names
TIMP2; DDC8; CSC-21K
Reactivity
Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Zebrafish. Others not known.
Applications
Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
TIMP2 (Tissue Inhibitor of Metalloproteinase 2), Antibody; TIMP2 (Tissue Inhibitor of Metalloproteinase 2); Metalloproteinase inhibitor 2; TIMP metallopeptidase inhibitor 2; TIMP-2; TIMP2; Tissue Inhibitor of Metalloproteinase 2; anti-TIMP2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Zebrafish. Others not known.
Clonality
Monoclonal
Isotype
IgG
Clone Number
TIMP2/2488R
Specificity
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
220
Applicable Applications for anti-TIMP2 antibody
IHC (Immunohistochemistry)
Immunogen
A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)
Positive Control
HeLa Cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.
Cellular Localization
Cytoplasm and Cell Surface
Chromosome Location
17q25
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified TIMP2 Rabbit Recombinant Monoclonal Antibody (TIMP2/2488R). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified TIMP2 Rabbit Recombinant Monoclonal Antibody (TIMP2/2488R). Confirmation of Purity and Integrity of Antibody.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Placenta stained with TIMP2 Rabbit Recombinant Monoclonal Antibody (TIMP2/2488R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Placenta stained with TIMP2 Rabbit Recombinant Monoclonal Antibody (TIMP2/2488R).)
Related Product Information for anti-TIMP2 antibody
Recombinant Rabbit Monoclonal Antibody
References
Jeffery et al. 2009. Histopathology. 54(7):820-8; Murray et al. 1998. Gut. 43(6):791-7.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21kDa
NCBI Official Full Name
metalloproteinase inhibitor 2
NCBI Official Synonym Full Names
TIMP metallopeptidase inhibitor 2
NCBI Official Symbol
TIMP2
NCBI Official Synonym Symbols
DDC8; CSC-21K
NCBI Protein Information
metalloproteinase inhibitor 2
UniProt Protein Name
Metalloproteinase inhibitor 2
UniProt Gene Name
TIMP2
UniProt Synonym Gene Names
TIMP-2
Similar Products
Product Notes
The TIMP2 timp2 (Catalog #AAA214825) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TIMP2 (Tissue Inhibitor of Metalloproteinase 2) reacts with Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Zebrafish. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's TIMP2 (Tissue Inhibitor of Metalloproteinase 2) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TIMP2 timp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIMP2 (Tissue Inhibitor of Metalloproteinase 2), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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