FCM/FACS (Flow Cytometry)
(Surface staining of normal human peripheral blood cells with CD284 antibody (PE) (left), and CD284 antibody (APC) (right).Appropriate Isotype Controls were used (open histogram). Cells in the monocyte population were used for analysis.)
Mouse anti-Human Toll-like receptor 4 Monoclonal Antibody | anti-TLR4 antibody
Toll-like receptor 4 antibody
Gene Names
TLR4; TOLL; CD284; TLR-4; ARMD10
Reactivity
Human
Applications
Functional Assay
Purity
Toll-like receptor 4 antibody was purified by affinity chromatography.
Synonyms
Toll-like receptor 4, Antibody; Toll-like receptor 4 antibody; Monoclonal Toll-like receptor 4; Anti-Toll-like receptor 4; Toll-like receptor 4; TLR-4; toll-like receptor 4; Toll-like receptor-4; anti-TLR4 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a kappa
Clone Number
HTA125
Specificity
Human
Purity/Purification
Toll-like receptor 4 antibody was purified by affinity chromatography.
Form/Format
Liquid in PBS, pH 7.2, with 0.09% Sodium Azide
Sequence Length
839
Applicable Applications for anti-TLR4 antibody
FA (Functional Assay)
Preparation and Storage
Store at 4°C.
FCM/FACS (Flow Cytometry)
(Surface staining of normal human peripheral blood cells with CD284 antibody (PE) (left), and CD284 antibody (APC) (right).Appropriate Isotype Controls were used (open histogram). Cells in the monocyte population were used for analysis.)
FCM/FACS (Flow Cytometry)
(Surface staining of normal human peripheral blood cells with CD284 antibody (PE) (left), and CD284 antibody (APC) (right).Appropriate Isotype Controls were used (open histogram). Cells in the monocyte population were used for analysis.)
Related Product Information for anti-TLR4 antibody
The HTA125 monoclonal antibody reacts with human Toll-like receptor 4. So far, at least ten members of the Toll family have been identified in humans. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR4 physically associates with another molecule called MD-2, and together with CD14, this complex is responsible for LPS recognition and signaling. TLR4 is expressed by peripheral blood monocytes. HTA125 has been reported to immunoprecipitate human TLR4 from transfected cells. Most TLR cell surface expression, especially TLR1 and TLR4, occurs at low levels on monocytes and at even lower levels on other cell types including granulocytes and immature dendritic cells. Furthermore, a relatively high degree of variability in TLR surface expression has been reported among normal donors.
Product Categories/Family for anti-TLR4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
toll-like receptor 4 isoform A
NCBI Official Synonym Full Names
toll-like receptor 4
NCBI Official Symbol
TLR4
NCBI Official Synonym Symbols
TOLL; CD284; TLR-4; ARMD10
NCBI Protein Information
toll-like receptor 4
UniProt Protein Name
Toll-like receptor 4
UniProt Gene Name
TLR4
UniProt Entry Name
TLR4_HUMAN
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Product Notes
The TLR4 tlr4 (Catalog #AAA107432) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Toll-like receptor 4 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Toll-like receptor 4 can be used in a range of immunoassay formats including, but not limited to, FA (Functional Assay). Researchers should empirically determine the suitability of the TLR4 tlr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Toll-like receptor 4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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