Mouse anti-Human TP63/p63 Monoclonal Antibody | anti-TP63 antibody
TP63/p63 Mouse anti-Human Monoclonal Antibody
Gene Names
TP63; AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B)
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry
Purity
Affinity purified
Synonyms
TP63/p63, Antibody; TP63/p63 Mouse anti-Human Monoclonal Antibody; PathPlus TP63/p63 Antibody; TP63; B(p51B); CUSP; AIS; EEC3; KET; NBP; OFC8; p73L; p73H; RHS; SHFM4; LMS; TP53CP; Tumor protein 63; Tumor protein p53-like; Tumor protein p73-like; TP73L; p51; B(p51A); Tumor protein p63; p40; p53CP; p63; TP53L; anti-TP63 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
PBS, 0.02% Sodium Azide, 50% Glycerol
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-TP63 antibody
WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Target
Human TP63/p63
Immunogen
Synthetic p63
Conjugation
Unconjugated
Family
Apoptosis
Preparation and Storage
Store at -20 degree C for up to 1 year.
Related Product Information for anti-TP63 antibody
P63 antibody is an unconjugated mouse monoclonal antibody to human p63 (TP63). Validated for IHC and WB.
TP63 is a nuclear transcription factor and member of the p53 family that is important for development of epithelial tissues. TP63 is a useful marker for distinguishing squamous cell carcinomas of the lung from adenocarcinomas or small cell carcinomas. TP63 is also expressed in basal epithelia (myoepithelial cells) of a number of tissues, including prostate and breast, and is useful for differentiating between benign (presence of myoepithelia) and malignant glands (lacking myoepithelial cells). The marker has high sensitivity and specificity in both primary and metastatic tumors. TP63 antibodies are often used alongside antibodies to NKX2-1 in immunohistochemistry to identify squamous carcinomas of the lung, head and neck as well as ruling out invasion in breast, prostate, and salivary gland cancers.
TP63 is a nuclear transcription factor and member of the p53 family that is important for development of epithelial tissues. TP63 is a useful marker for distinguishing squamous cell carcinomas of the lung from adenocarcinomas or small cell carcinomas. TP63 is also expressed in basal epithelia (myoepithelial cells) of a number of tissues, including prostate and breast, and is useful for differentiating between benign (presence of myoepithelia) and malignant glands (lacking myoepithelial cells). The marker has high sensitivity and specificity in both primary and metastatic tumors. TP63 antibodies are often used alongside antibodies to NKX2-1 in immunohistochemistry to identify squamous carcinomas of the lung, head and neck as well as ruling out invasion in breast, prostate, and salivary gland cancers.
References
Conde, 2010; Rekhtman, 2011; Kalhor, 2006.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
65,288 Da
NCBI Official Full Name
tumor protein 63 isoform 1
NCBI Official Synonym Full Names
tumor protein p63
NCBI Official Symbol
TP63
NCBI Official Synonym Symbols
AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B)
NCBI Protein Information
tumor protein 63
UniProt Protein Name
Tumor protein 63
UniProt Gene Name
TP63
UniProt Synonym Gene Names
KET; P63; P73H; P73L; TP73L; p63; CUSP; TP63; p73L
UniProt Entry Name
P63_HUMAN
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Product Notes
The TP63 tp63 (Catalog #AAA163088) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TP63/p63 Mouse anti-Human Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TP63/p63 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TP63 tp63 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TP63/p63, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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