IHC (Immunohistochemistry)
(Anti-UMOD / Uromodulin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.)
Mouse anti-Dog, Human UMOD / Uromodulin Monoclonal Antibody | anti-UMOD antibody
Mouse Monoclonal [clone 10.32] (IgG2b) to Human UMOD / Uromodulin
Gene Names
UMOD; THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2
Reactivity
Dog, Human
Applications
Immunohistochemistry
Purity
Protein G Purified
Synonyms
UMOD / Uromodulin, Antibody; Mouse Monoclonal [clone 10.32] (IgG2b) to Human UMOD / Uromodulin; Anti-UMOD / Uromodulin Antibody (clone 10.32, FITC) IHC-plus; UMOD; ADMCKD2; FJHN; HNFJ; MCKD2; THGP; THP; Uromucoid; Tamm-Horsfall glycoprotein; HNFJ1; Uromodulin; Human UMOD; anti-UMOD antibody
Host
Mouse
Reactivity
Dog, Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
10.32
Specificity
Anti-human Tamm-Horsfall protein (THP) is a monoclonal antibody which reacts with an epitope of the urinary mucoprotein. Tamm-Horsfall protein is a glycoprotein of approximately 80 kD containing up to 25% carbohydrate by weight.
Purity/Purification
Protein G Purified
Form/Format
PBS, 0.02% sodium azide, EIA grade BSA. Sourced in Ascites.
Concentration
0.1 mg/ml (varies by lot)
Sequence Length
640
Applicable Applications for anti-UMOD antibody
IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Human Tamm-Horsfall protein
Immunogen Type
Purified protein
Antibody Modification
FITC
Target
Human UMOD / Uromodulin
Conjugations
Fluorescein (FITC)
Immunogen Species
UMOD / Uromodulin antibody was raised against human
Preparation and Storage
Short term 4 C, Long term -20 C, Product is photosensitive and should be protected from light. Avoid freeze-thaw cycles.
IHC (Immunohistochemistry)
(Anti-UMOD / Uromodulin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.)
IHC (Immunohistochemistry)
(Anti-UMOD / Uromodulin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.)
Related Product Information for anti-UMOD antibody
This product is a monoclonal antibody which reacts with an epitope of the urinary mucoprotein. Tamm-Horsfall protein is a glycoprotein of approximately 80 kDa containing up to 25% carbohydrate by weight. It exists as a high molecular weight polymer in urine and approximately 50 mg of the THP are excreted per day by adult humans. THP is produced by the epithelial cells lining the thick ascending loop of Henle and distal convoluted tubules of the kidney. THP is also the primary constituent of renal tubular casts and THP aggregation has been implicatedas a factor in the pathogenesis of acute renal failure by causing tubular . obstruction. Antibody to THP is present in the serum of patients with pyelonephritis and reflus uropathy. This monoclonal antibody has shown good localization to the distal tubule and collecting duct as well as to large deposits of Tamm-Horsfall protein which has clogged peri-pelvic veins. This antibody also works with canine. Total protein concentration (including BSA) is 4-5 mg/ml.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
~80kDa
NCBI Official Full Name
uromodulin isoform a preproprotein
NCBI Official Synonym Full Names
uromodulin
NCBI Official Symbol
UMOD
NCBI Official Synonym Symbols
THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2
NCBI Protein Information
uromodulin; uromucoid; Tamm-Horsfall urinary glycoprotein
UniProt Protein Name
Uromodulin
UniProt Gene Name
UMOD
UniProt Synonym Gene Names
THP
UniProt Entry Name
UROM_HUMAN
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Product Notes
The UMOD umod (Catalog #AAA51843) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 10.32] (IgG2b) to Human UMOD / Uromodulin reacts with Dog, Human and may cross-react with other species as described in the data sheet. AAA Biotech's UMOD / Uromodulin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the UMOD umod for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UMOD / Uromodulin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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