Vimentin Recombinant Antibody | VIM recombinant antibody

Recombinant Anti-Vimentin Antibody, Rabbit Monoclonal

Cat. Num. AAA259396

• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Protein A
• Synonyms: Vimentin, Recombinant Antibody; Recombinant Anti-Vimentin Antibody, Rabbit Monoclonal; Vimentin Antibody, Rabbit MAb; vimentin; VIM recombinant antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone Number: 013
• Specificity: Human Vimentin
• Purity/Purification: Protein A
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for VIM recombinant antibody: IHC (Immunohistochemistry)
• Immunogen: Recombinant Human Vimentin Protein ( P08670; Met1-Glu466).
• Preparation and Storage: This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.; This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

IHC (Immunohistochemisry)

(Immunochemical staining of human Vimentin in human kidney with rabbit monoclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)

IHC (Immunohiostchemistry)

(Immunochemical staining of human Vimentin in human thyroid gland with rabbit monoclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)

IHC (Immunohistochemistry)

(Immunochemical staining of human Vimentin in human small intestine with rabbit monoclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.)

Related Product Information for VIM recombinant antibody

Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central alpha-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. Therefore, in general, it is accepted that vimentin is the cytoskeletal component responsible for maintaining cell integrity. Vimentin is also responsible for stabilizing cytoskeletal interactions. It is found that vimentin control the transport of low-density lipoprotein. It has been used as a sarcoma tumor marker to identify mesenchyme.

References

Russel. RL. e. al. (2001. Uridin. phosphorylas. associatio. wit. vimentin. Intracellula. distributio. an. localization. . Bio. Chem. 276(16):13302-7.Moinova. e. al. (2012. Aberran. Vimenti. Methylatio. i. Characteristi. o. Uppe. G. Pathologies. Cance. Epidemiolog. Biomarker. Prev. 21(4):594-600.Leade. M. e. al. (1987. Vimentin. a. evaluatio. o. it. rol. a. . tumou. marker. Histopathology. 11(1):63-72.

NCBI and Uniprot Product Information

• NCBI GI #: 62414289
• NCBI GeneID: 7431
• NCBI Accession #: NP_003371.2
• NCBI GenBank Nucleotide #: NM_003380.3
• UniProt Accession #: P08670; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3; B0YJC2; D3DRU4
• Molecular Weight: 53,652 Da
• NCBI Official Full Name: vimentin
• NCBI Official Synonym Full Names: vimentin
• NCBI Official Symbol: VIM
• NCBI Protein Information: vimentin
• UniProt Protein Name: Vimentin
• UniProt Gene Name: VIM
• UniProt Entry Name: VIME_HUMAN