IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human Breast tissues using anti-ZBTB7B antibody)
Mouse ZBTB7B Monoclonal Antibody | anti-ZBTB7B antibody
ZBTB7B antibody
Gene Names
ZBTB7B; CKROX; THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B
Applications
Western Blot, Immunofluorescence, ELISA
Synonyms
ZBTB7B, Antibody; ZBTB7B antibody; Monoclonal ZBTB7B; Anti-ZBTB7B; ZBTBB-7; ZBTBB 7; Zinc finger and BTB domain-containing protein 7B; ZBTB7B; anti-ZBTB7B antibody
Host
Mouse
Clonality
Monoclonal
Isotype
lgG1
Clone Number
7C12
Form/Format
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
539
Applicable Applications for anti-ZBTB7B antibody
WB (Western Blot), IF (Immunofluorescence), ELISA
Biological Significance
ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.
Cross-Reactivity
Human
Immunogen
ZBTB7B antibody was raised in Mouse using a purified recombinant fragment of human ZBTB7B expressed in E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human Breast tissues using anti-ZBTB7B antibody)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human Breast tissues using anti-ZBTB7B antibody)
WB (Western Blot)
(Western Blot showing ZBTB7B antibody used against HEK293 (1,2) cell lysate.)
WB (Western Blot)
(Western Blot showing ZBTB7B antibody used against HEK293 (1,2) cell lysate.)
Related Product Information for anti-ZBTB7B antibody
Mouse monoclonal ZBTB7B antibody
Product Categories/Family for anti-ZBTB7B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61,584 Da
NCBI Official Full Name
zinc finger and BTB domain-containing protein 7B isoform 1
NCBI Official Synonym Full Names
zinc finger and BTB domain containing 7B
NCBI Official Symbol
ZBTB7B
NCBI Official Synonym Symbols
CKROX; THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B
NCBI Protein Information
zinc finger and BTB domain-containing protein 7B
UniProt Protein Name
Zinc finger and BTB domain-containing protein 7B
UniProt Gene Name
ZBTB7B
UniProt Synonym Gene Names
ZBTB15; ZFP67; ZNF857B; hcKrox; Zfp-67
UniProt Entry Name
ZBT7B_HUMAN
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Product Notes
The ZBTB7B zbtb7b (Catalog #AAA106302) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ZBTB7B can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence), ELISA. Researchers should empirically determine the suitability of the ZBTB7B zbtb7b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZBTB7B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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