IL11 active protein
IL11 protein (Mouse)
Gene Names
IL11; AGIF; IL-11
Purity
> 98% by SDS-PAGE and HPLC analysis
Synonyms
IL11; N/A; IL11 protein (Mouse); Interleukin 11 protein; AGIF protein; IL 11 protein; IL-11 protein; IL-11; Adipogenesis inhibitory factor protein; IL 11; IL11 active protein
Host
Mouse
Purity/Purification
> 98% by SDS-PAGE and HPLC analysis
Form/Format
0.2um filtered solution, lyophilized with no additives. Centrtifuge vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Concentration
10ug/vial; Lyophilized (varies by lot)
Sequence
Region of IL11 protein corresponds to amino acids MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL.
Sequence Length
199
Protein Type
Recombinant
Biological Significance
IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.
Biological Activity
Determined by its ability to stimulate the proliferation of mouse T11 cells. The expected ED50 is <2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
Biohazard
Not for human use. Use normal laboratory precautions when handling reagent. For research purposes only.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Source
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for IL11 active protein
Purified recombinant Mouse IL11 protein
Product Categories/Family for IL11 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19.1 kDa
NCBI Official Full Name
interleukin-11 isoform 1
NCBI Official Synonym Full Names
interleukin 11
NCBI Official Symbol
IL11
NCBI Official Synonym Symbols
AGIF; IL-11
NCBI Protein Information
interleukin-11
UniProt Protein Name
Interleukin-11
UniProt Gene Name
IL11
UniProt Synonym Gene Names
AGIF
UniProt Entry Name
IL11_HUMAN
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Product Notes
The IL11 il11 (Catalog #AAA75591) is an Active Protein produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Region of IL11 protein correspond s to amino acids MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL. It is sometimes possible for the material contained within the vial of "IL11, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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