<
SDS_PAGE
(SDS-PAGE Analysis Purified Aurora B Recombinant Mouse Monoclonal Antibody (rAURKB/1592). Confirmation of Integrity and Purity of Antibody.)
Mouse anti-Human Aurora B Antibody | anti-AURKB antibody
Aurora B (Proliferation Marker)
Gene Names
AURKB; AIK2; AIM1; ARK2; AurB; IPL1; STK5; AIM-1; ARK-2; STK-1; STK12; PPP1R48; aurkb-sv1; aurkb-sv2
Reactivity
Human
Applications
Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
Aurora B; N/A; Aurora B (Proliferation Marker); AIK2; AIM-1; ARK-2; AurB; AURKB; Aurora-1; Aurora and Ipl1 like midbody associated protein 1; Aurora kinase B; Aurora-B; Aurora-related kinase 2; Aurora/IPL1-related kinase 2; IPL1; Protein phosphatase 1 regulatory subunit 48 (PPP1R48); Serine/threonine-protein kinase 12; Serine/threonine-protein kinase aurora-B; STK1; STK12; STK5; anti-AURKB antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1, kappa
Clone Number
rAURKB/1592
Specificity
Recognizes a protein of 39kDa, which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
344
Applicable Applications for anti-AURKB antibody
IHC (Immunohistochemistry)
Positive Control
HeLa cells. Tonsil, Placenta, Hodgkin s Lymphoma or Colon Carcinoma.
Immunogen
Recombinant fragment (around aa 89-251) of human Aurora B protein (exact sequence is proprietary)
Cellular Localization
Nuclear and Cytoplasmic
Hu-chromosome Location
17p13.1
Antibody Type
Recombinant Mouse Monoclonal Antibody
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS_PAGE
(SDS-PAGE Analysis Purified Aurora B Recombinant Mouse Monoclonal Antibody (rAURKB/1592). Confirmation of Integrity and Purity of Antibody.)
SDS_PAGE
(SDS-PAGE Analysis Purified Aurora B Recombinant Mouse Monoclonal Antibody (rAURKB/1592). Confirmation of Integrity and Purity of Antibody.)
IHC (Immunohistochemisry)
(Formalin-fixed, paraffin-embedded human placenta stained with Aurora B Recombinant Mouse Monoclonal Antibody (rAURKB/1592).)
IHC (Immunohistochemisry)
(Formalin-fixed, paraffin-embedded human placenta stained with Aurora B Recombinant Mouse Monoclonal Antibody (rAURKB/1592).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human kidney stained with Aurora B Recombinant Mouse Monoclonal Antibody (rAURKB/1592).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human kidney stained with Aurora B Recombinant Mouse Monoclonal Antibody (rAURKB/1592).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human kidney stained with Aurora B Recombinant Mouse Monoclonal Antibody (rAURKB/1592).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human kidney stained with Aurora B Recombinant Mouse Monoclonal Antibody (rAURKB/1592).)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39kDa
NCBI Official Full Name
aurora kinase B isoform 1
NCBI Official Synonym Full Names
aurora kinase B
NCBI Official Symbol
AURKB
NCBI Official Synonym Symbols
AIK2; AIM1; ARK2; AurB; IPL1; STK5; AIM-1; ARK-2; STK-1; STK12; PPP1R48; aurkb-sv1; aurkb-sv2
NCBI Protein Information
aurora kinase B
UniProt Protein Name
Aurora kinase B
UniProt Gene Name
AURKB
UniProt Synonym Gene Names
AIK2; AIM1; AIRK2; ARK2; STK1; STK12; STK5; AIM-1; ARK-2
UniProt Entry Name
AURKB_HUMAN
Similar Products
Product Notes
The AURKB aurkb (Catalog #AAA215288) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Aurora B (Proliferation Marker) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Aurora B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the AURKB aurkb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Aurora B, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.