Mouse Coagulation Factor Vii, F7 ELISA Kit | F7 elisa kit
Mouse Coagulation Factor Vii, F7 Primacu ELISA Kit
Gene Names
F7; Cf7; FVII; mfVII; AI132620
Reactivity
Mouse
Synonyms
Coagulation Factor Vii, F7; N/A; Mouse Coagulation Factor Vii, F7 Primacu ELISA Kit; Coagulation factor VII; Factor VII; Cf7; F7 elisa kit
Reactivity
Mouse
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
31.25-2000pg/mL
Sensitivity
10.38pg/mL
Standard Solution
16ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Related Product Information for F7 elisa kit
Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class, and Factor VII (FVII) deficiency is the most frequent among rare congenital bleeding disorders. Factor VII contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. The main role of factor VII is to initiate the process of coagulation in conjunction with tissue factor (TF). Tissue factor is found on the outside of blood vessels, normally not exposed to the blood stream. The action of the Factor VII is impeded by tissue factor pathway inhibitor (TFPI), which is released almost immediately after initiation of coagulation. Factor VII is vitamin K dependent and is produced in the liver. Upon vessel injury, tissue factor is exposed to the blood and circulating Factor VII. Once bound to TF, FVII is activated to FVIIa by different proteases, among which are thrombin (factor IIa), factor Xa, IXa, XIIa, and the FVIIa-TF complex itself. Recombinant activated factor VII (rFVIIa) is a haemostatic agent, which was originally developed for the treatment of haemophilia patients with inhibitors against factor FVIII or FIX. FVIIa binds specifically to endothelial protein C receptor (EPCR), a known cellular receptor for protein C and activated protein C, on the endothelium. rFVIIa is a novel hemostatic agent, originally developed for the treatment of hemorrhage in hemophiliacs with inhibitors, which has been successfully used recently in an increasing number of nonhemophilic bleeding conditions.
Product Categories/Family for F7 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
160,000
NCBI Official Full Name
coagulation factor VII
NCBI Official Synonym Full Names
coagulation factor VII
NCBI Official Symbol
F7
NCBI Official Synonym Symbols
Cf7; FVII; mfVII; AI132620
NCBI Protein Information
coagulation factor VII; serum prothrombin conversion accelerator
UniProt Protein Name
Coagulation factor VII
UniProt Gene Name
F7
UniProt Synonym Gene Names
Cf7
UniProt Entry Name
FA7_MOUSE
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Product Notes
The Mouse F7 f7 (Catalog #AAA124290) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124290 ELISA Kit recognizes Mouse F7. It is sometimes possible for the material contained within the vial of "Coagulation Factor Vii, F7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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