Mouse Prostatic Acid Phosphatase, Acp3 ELISA Kit | Acp3 elisa kit
Mouse Prostatic Acid Phosphatase, Acp3 Primacu ELISA Kit
Gene Names
Acpp; Lap; PAP; FRAP; Ppal; 5'-NT; A030005E02Rik
Reactivity
Mouse
Synonyms
Prostatic Acid Phosphatase, Acp3; N/A; Mouse Prostatic Acid Phosphatase, Acp3 Primacu ELISA Kit; Prostatic acid phosphatase; Prostatic Acid Phosphatase; Acpp; Acp3 elisa kit
Reactivity
Mouse
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
156.25-10000pg/mL
Sensitivity
39.46pg/mL
Standard Solution
100ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Related Product Information for Acp3 elisa kit
Prostatic acid phosphatase (PAP, or ACPP), also known as prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. As a non-specific phosphomonoesterase, Prostatic acid phosphatase is synthesized and secreted into seminal plasma under androgenic control. The enzyme is a dimer of molecular weight around 100 kDa. Prostatic acid phosphatase is a clinically important protein for its relevance as a biomarker of prostate carcinoma. Furthermore, it has a potential role in fertilization. The major action of PAP is to dephosphorylate macromolecules with the help of catalytic residues (His(12) and Asp(258)) that are located in the cleft between two domains. Cellular prostatic acid phosphatase (cPAcP), an authentic tyrosine phosphatase, is proposed to function as a negative growth regulator of prostate cancer (PCa) cells in part through its dephosphorylation of ErbB-2. cPAcP functions as a neutral protein tyrosine phosphatase (PTP) in prostate cancer cells and dephosphorylates HER-2/ErbB-2/Neu (HER-2: human epidermal growth factor receptor-2) at the phosphotyrosine (p-Tyr) residues. Injection of the secretory isoform of PAP has potent antinociceptive effects in mouse models of chronic pain. This enzyme exhibits ecto-5'-nucleotidase activity, is widely distributed, and implicated in the formation of chronic pain. Additionally, PAP could be a target molecule in specific immunotherapy for patients with nonprostate adenocarcinomas including colon and gastric cancers.
Product Categories/Family for Acp3 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,863 Da
NCBI Official Full Name
prostatic acid phosphatase isoform 2
NCBI Official Synonym Full Names
acid phosphatase, prostate
NCBI Official Symbol
Acpp
NCBI Official Synonym Symbols
Lap; PAP; FRAP; Ppal; 5'-NT; A030005E02Rik
NCBI Protein Information
prostatic acid phosphatase
UniProt Protein Name
Prostatic acid phosphatase
UniProt Gene Name
Acpp
UniProt Synonym Gene Names
5'-NT; FRAP; TMPase
UniProt Entry Name
PPAP_MOUSE
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Product Notes
The Mouse Acp3 acpp (Catalog #AAA124114) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124114 ELISA Kit recognizes Mouse Acp3. It is sometimes possible for the material contained within the vial of "Prostatic Acid Phosphatase, Acp3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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