IF (Immunofluorescence)
(Figure 2. Immunofluorescence analysis of Hela cells using GSK3 alpha mouse mAb showing cytoplasmic localization.)
Mouse anti-Human GSK3 alpha Antibody | anti-GSK3 alpha antibody
GSK3 alpha Antibody
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Synonyms
GSK3 alpha; N/A; GSK3 alpha Antibody; DKFZp686D0638; GSK3A; anti-GSK3 alpha antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
9D5G1
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
483
Applicable Applications for anti-GSK3 alpha antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of GSK3 alpha expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C
IF (Immunofluorescence)
(Figure 2. Immunofluorescence analysis of Hela cells using GSK3 alpha mouse mAb showing cytoplasmic localization.)
IF (Immunofluorescence)
(Figure 2. Immunofluorescence analysis of Hela cells using GSK3 alpha mouse mAb showing cytoplasmic localization.)
WB (Western Blot)
(Figure 1. Western blot analysis using GSK3 alpha mouse mAb against Hela (1) and PC-3 cell lysate.)
WB (Western Blot)
(Figure 1. Western blot analysis using GSK3 alpha mouse mAb against Hela (1) and PC-3 cell lysate.)
Related Product Information for anti-GSK3 alpha antibody
Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily; GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.
Product Categories/Family for anti-GSK3 alpha antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,981 Da
NCBI Official Full Name
glycogen synthase kinase-3 alpha
NCBI Official Synonym Full Names
glycogen synthase kinase 3 alpha
NCBI Official Symbol
GSK3A
NCBI Protein Information
glycogen synthase kinase-3 alpha
UniProt Protein Name
Glycogen synthase kinase-3 alpha
UniProt Gene Name
GSK3A
UniProt Synonym Gene Names
GSK-3 alpha
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Product Notes
The GSK3 alpha gsk3a (Catalog #AAA108431) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GSK3 alpha Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GSK3 alpha can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GSK3 alpha gsk3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GSK3 alpha, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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