IHC (Immunohistochemisry)
(Figure 3. Immunohistochemical analysis of paraffin-embedded brain tissues (left) and pancreas tissues (right) using KLHL13 mouse mAb with DAB staining.)
Mouse anti-Human KLHL13 Antibody | anti-KLHL13 antibody
KLHL13 Antibody
Gene Names
KLHL13; BKLHD2
Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, Western Blot
Synonyms
KLHL13; N/A; KLHL13 Antibody; BKLHD2; FLJ10262; MGC74791; anti-KLHL13 antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
8D1
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
658
Applicable Applications for anti-KLHL13 antibody
ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of human KLHL13 expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C
IHC (Immunohistochemisry)
(Figure 3. Immunohistochemical analysis of paraffin-embedded brain tissues (left) and pancreas tissues (right) using KLHL13 mouse mAb with DAB staining.)
IHC (Immunohistochemisry)
(Figure 3. Immunohistochemical analysis of paraffin-embedded brain tissues (left) and pancreas tissues (right) using KLHL13 mouse mAb with DAB staining.)
IF (Immunofluorescence)
(Figure 2. Immunofluorescence analysis of NTERA-2 cells (left) and U251 (right) cells using KLHL13 mouse mAb (green). Blue. DRAQ5 fluorescent DNA dye. Red. Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
IF (Immunofluorescence)
(Figure 2. Immunofluorescence analysis of NTERA-2 cells (left) and U251 (right) cells using KLHL13 mouse mAb (green). Blue. DRAQ5 fluorescent DNA dye. Red. Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
WB (Western Blot)
(Figure 1. Western blot analysis using KLHL13 mouse mAb against Hela (1) and MCF-7 (2) cell lysate.)
WB (Western Blot)
(Figure 1. Western blot analysis using KLHL13 mouse mAb against Hela (1) and MCF-7 (2) cell lysate.)
Related Product Information for anti-KLHL13 antibody
KLHL13 (kelch-like 13), also known as BKLHD2 (BTB and kelch domain-containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Via its BTB and C-terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL-3 ligase.
Product Categories/Family for anti-KLHL13 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74kDa
NCBI Official Full Name
kelch-like protein 13 isoform b
NCBI Official Synonym Full Names
kelch like family member 13
NCBI Official Symbol
KLHL13
NCBI Official Synonym Symbols
BKLHD2
NCBI Protein Information
kelch-like protein 13
UniProt Protein Name
Kelch-like protein 13
UniProt Gene Name
KLHL13
UniProt Synonym Gene Names
BKLHD2; KIAA1309
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Product Notes
The KLHL13 klhl13 (Catalog #AAA108820) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The KLHL13 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KLHL13 can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the KLHL13 klhl13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLHL13, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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