Mouse anti-Human LIME1 Antibody | anti-LIME1 antibody
Anti-LIME1 Purified
Gene Names
LIME1; LIME; dJ583P15.4
Reactivity
Human
Applications
Immunoprecipitation
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
LIME1; N/A; Anti-LIME1 Purified; Lck interacting transmembrane adaptor 1; LITA1; anti-LIME1 antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
LIME-06
Specificity
The antibody LIME-06 was raised against intracellular fragment corresponding to aa 141-295 of human LIME, a 30 kDa Lck-interacting transmembrane adaptor expressed by T cells.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
295
Applicable Applications for anti-LIME1 antibody
IP (Immunoprecipitation)
Immunogen
Bacterially expressed intracellular fragment corresponding to aa 141-295 of human LIME.
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-LIME1 antibody
LIME (Lck-interacting molecule) is a 30 kDa double-palmitoylated protein with unusually basic cytoplasmic domain, expressed by T cells. After ligation of CD4 or CD8 T cell coreceptors, LIME is phosphorylated by Src-family kinases and associates with Lck and Fyn kinases and with their negative regulator Csk. Interestingly, Csk-mediated phosphorylation of C-terminal negative-regulatory tyrosine of LIME-associated Lck can result in increase of enzymatic activity compared with the total pool of Lck, thus, LIME serves as a positive regulator of TCR-dependent T cell signaling. However, under some circumstances, LIME may mediate inhibitory signals.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
lck-interacting transmembrane adapter 1 isoform 1
NCBI Official Synonym Full Names
Lck interacting transmembrane adaptor 1
NCBI Official Symbol
LIME1
NCBI Official Synonym Symbols
LIME; dJ583P15.4
NCBI Protein Information
lck-interacting transmembrane adapter 1
UniProt Protein Name
Lck-interacting transmembrane adapter 1
UniProt Gene Name
LIME1
UniProt Synonym Gene Names
LIME; Lck-interacting membrane protein
UniProt Entry Name
LIME1_HUMAN
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Product Notes
The LIME1 lime1 (Catalog #AAA128662) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-LIME1 Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LIME1 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation). Researchers should empirically determine the suitability of the LIME1 lime1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LIME1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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