Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
3G9H7; 4H12E9
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
340
Applicable Applications for anti-PAR4 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C
Related Product Information for anti-PAR4 antibody
Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.
Product Categories/Family for anti-PAR4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,568 Da
NCBI Official Full Name
PRKC apoptosis WT1 regulator protein isoform 1
NCBI Official Synonym Full Names
pro-apoptotic WT1 regulator
NCBI Official Symbol
PAWR
NCBI Official Synonym Symbols
PAR4; Par-4
NCBI Protein Information
PRKC apoptosis WT1 regulator protein
UniProt Protein Name
PRKC apoptosis WT1 regulator protein
UniProt Gene Name
PAWR
UniProt Synonym Gene Names
PAR4; Par-4
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Product Notes
The PAR4 pawr (Catalog #AAA108611) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PAR4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PAR4 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PAR4 pawr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAR4, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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