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product-image-AAA108434_IHC13.jpg IHC (Immunohiostchemistry) (Figure 2. Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using PYK2 mouse mAb.)

Mouse anti-Human PYK2 Antibody | anti-PYK2 antibody

PYK2 Antibody

Gene Names
PTK2B; PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Synonyms
PYK2; N/A; PYK2 Antibody; PKB; PTK; CAKB; FAK2; FRNK; PTK2B; anti-PYK2 antibody
Ordering
Host
Mouse
Reactivity
Human
Isotype
IgG2a
Clone Number
5E2D5
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
1009
Applicable Applications for anti-PYK2 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of PYK2 (aa815-997) expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C

IHC (Immunohiostchemistry)

(Figure 2. Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using PYK2 mouse mAb.)

product-image-AAA108434_IHC13.jpg IHC (Immunohiostchemistry) (Figure 2. Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using PYK2 mouse mAb.)

WB (Western Blot)

(Figure 1. Western blot analysis using PYK2 mouse mAb against Raji (1), PMA induced THP-1 (2), Jurkat (3) and Ramos (4) cell lysate.)

product-image-AAA108434_WB15.jpg WB (Western Blot) (Figure 1. Western blot analysis using PYK2 mouse mAb against Raji (1), PMA induced THP-1 (2), Jurkat (3) and Ramos (4) cell lysate.)
Related Product Information for anti-PYK2 antibody
PYK2. PTK2B protein tyrosine kinase 2 beta, also known as PTK2B, PKB, PTK, CAKB, FAK2, FRNK. Entrez Protein NP_004094. It is a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
115.8kDa
NCBI Official Full Name
protein-tyrosine kinase 2-beta isoform a
NCBI Official Synonym Full Names
protein tyrosine kinase 2 beta
NCBI Official Symbol
PTK2B
NCBI Official Synonym Symbols
PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK
NCBI Protein Information
protein-tyrosine kinase 2-beta
UniProt Protein Name
Protein-tyrosine kinase 2-beta
UniProt Gene Name
PTK2B
UniProt Synonym Gene Names
FAK2; PYK2; RAFTK; CADTK; CAK-beta; CAKB; FADK 2; RAFTK

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Product Notes

The PYK2 ptk2b (Catalog #AAA108434) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PYK2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PYK2 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PYK2 ptk2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PYK2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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