IF (Immunofluorescence)
(Figure 4. Confocal immunofluorescence analysis of PANC-1 cells using SORL1 mouse mAb (green). Red. Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue. DRAQ5 fluorescent DNA dye.)
Mouse anti-Human SORL1 Antibody | anti-SORL1 antibody
SORL1 Antibody
Gene Names
SORL1; LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32
Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry
Synonyms
SORL1; N/A; SORL1 Antibody; anti-SORL1 antibody
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
3B6B11
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
2214
Applicable Applications for anti-SORL1 antibody
ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry)
Immunogen
Purified recombinant fragment of human SORL1 expressed in E. Coli.
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Figure 4. Confocal immunofluorescence analysis of PANC-1 cells using SORL1 mouse mAb (green). Red. Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue. DRAQ5 fluorescent DNA dye.)
IF (Immunofluorescence)
(Figure 4. Confocal immunofluorescence analysis of PANC-1 cells using SORL1 mouse mAb (green). Red. Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue. DRAQ5 fluorescent DNA dye.)
IHC (Immunohiostchemistry)
(Figure 2. Immunohistochemical analysis of paraffin-embedded human cerebrum tissues using SORL1 mouse mAb with DAB staining.)
IHC (Immunohiostchemistry)
(Figure 2. Immunohistochemical analysis of paraffin-embedded human cerebrum tissues using SORL1 mouse mAb with DAB staining.)
WB (Western Blot)
(Figure 1. Western blot analysis using SORL1 mouse mAb against truncated SORL1 recombinant protein.)
WB (Western Blot)
(Figure 1. Western blot analysis using SORL1 mouse mAb against truncated SORL1 recombinant protein.)
Related Product Information for anti-SORL1 antibody
SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.
Product Categories/Family for anti-SORL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
sortilin-related receptor preproprotein
NCBI Official Synonym Full Names
sortilin related receptor 1
NCBI Official Symbol
SORL1
NCBI Official Synonym Symbols
LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32
NCBI Protein Information
sortilin-related receptor
UniProt Protein Name
Sortilin-related receptor
UniProt Gene Name
SORL1
UniProt Synonym Gene Names
C11orf32; LDLR relative with 11 ligand-binding repeats; LR11; SorLA
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Product Notes
The SORL1 sorl1 (Catalog #AAA108721) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SORL1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SORL1 can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the SORL1 sorl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SORL1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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