Mouse SYK Antibody | anti-SYK antibody
Anti-SYK Purified
Gene Names
SYK; p72-Syk
Reactivity
Human, Rat, Mouse
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Immunoprecipitation
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
SYK; N/A; Anti-SYK Purified; spleen associated tyrosine kinase; p72Syk; anti-SYK antibody
Host
Mouse
Reactivity
Human, Rat, Mouse
Isotype
IgG1
Clone Number
SYK-01
Specificity
The antibody SYK-01 reacts with protein tyrosine kinase p72Syk (Syk; an intracellular antigen), which is required for the transduction of signals through the B cell antigen receptor (BCR) and the high affinity IgE receptor (FcepsilonRI).
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
612
Applicable Applications for anti-SYK antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot), IP (Immunoprecipitation)
Immunogen
Recombinant fragment (aa 5-360) of human Syk.
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-SYK antibody
Syk is a cytoplasmic protein tyrosine kinase that translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes. Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases. These kinases also help to activate Syk by phosphorylation of its activation loop.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
tyrosine-protein kinase SYK isoform Syk(S)
NCBI Official Synonym Full Names
spleen associated tyrosine kinase
NCBI Official Symbol
SYK
NCBI Official Synonym Symbols
p72-Syk
NCBI Protein Information
tyrosine-protein kinase SYK
UniProt Protein Name
Tyrosine-protein kinase SYK
UniProt Gene Name
SYK
UniProt Entry Name
KSYK_HUMAN
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Product Notes
The SYK syk (Catalog #AAA128968) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-SYK Purified reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SYK can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the SYK syk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYK, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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