Mouse anti-Human Catenin, gamma Antibody | anti-JUP antibody

Catenin, gamma (Cardiomyocyte Marker)

Cat. Num. AAA215048

• Gene Names: JUP; DP3; PDGB; PKGB; CTNNG; DPIII
• Reactivity: Human
• Applications: Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay, ELISA
• Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: Catenin, gamma; N/A; Catenin, gamma (Cardiomyocyte Marker); ARVD12; Catenin (cadherin-associated protein); gamma 80kDa; Catenin gamma; CTNNG; Desmoplakin III; Desmoplakin-3; DP3; DPIII; Junction Plakoglobin; PDGB; PKGB; anti-JUP antibody

• Host: Mouse
• Reactivity: Human
• Isotype: IgG1, kappa
• Clone Number: rCTNG/1664
• Specificity: It recognizes a protein of 80-87kDa, identified as gamma-catenin. The catenins (-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 745

• Applicable Applications for anti-JUP antibody: WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), ELISA
• Positive Control: A431, T47D or MCF-7 cells. Skin.
• Immunogen: Recombinant human gamma catenin protein
• Cellular Localization: Cell Surface and Cytoplasmic
• Hu-chromosome Location: 17q21
• Antibody Type: Recombinant Mouse Monoclonal Antibody
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C.; Antibody without azide: store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

FCM/FACS (Flow Cytometry)

(Flow Cytometric Analysis of PFA-fixed MCF-7 cells using Catenin, gamma Mouse Monoclonal Antibody (rCTNG/1664) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).)

IF (Immunofluorescence)

(Immunofluorescence staining of PFA-fixed HepG2 cells with Catenin, gamma Mouse Monoclonal Antibody (rCTNG/1664) followed by goat anti-Mouse IgG-CF488 (Green). Nuclei are labeled with Reddot (Red).)

IF (Immunofluorescence)

(Immunofluorescence staining of PFA-fixed MCF-7 cells with Catenin, gamma Mouse Monoclonal Antibody (rCTNG/1664) followed by goat anti-Mouse IgG-CF488 (Green). Nuclei are labeled with Reddot (Red).)

References

Janssens, B., et al. 2001. T-Catenin: a novel tissue-specific -cateninbinding protein mediating strong cell-cell adhesion. J. Cell Sci. 114:3177-3188

NCBI and Uniprot Product Information

• NCBI GI #: 4504811
• NCBI GeneID: 3728
• NCBI Accession #: NP_002221.1
• NCBI GenBank Nucleotide #: NP_002221.1
• UniProt Accession #: P14923
• Molecular Weight: 80-87kDa
• NCBI Official Full Name: junction plakoglobin
• NCBI Official Synonym Full Names: junction plakoglobin
• NCBI Official Symbol: JUP
• NCBI Official Synonym Symbols: DP3; PDGB; PKGB; CTNNG; DPIII
• NCBI Protein Information: junction plakoglobin
• UniProt Protein Name: Junction plakoglobin
• UniProt Gene Name: JUP
• UniProt Synonym Gene Names: CTNNG; DP3
• UniProt Entry Name: PLAK_HUMAN