Pantothenate kinase 2, mitochondrial (PANK2) Recombinant Protein | PANK2 recombinant protein
Recombinant Human Pantothenate kinase 2, mitochondrial (PANK2)
Gene Names
PANK2; HSS; HARP; PKAN; NBIA1; C20orf48
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Pantothenate kinase 2, mitochondrial (PANK2); N/A; Recombinant Human Pantothenate kinase 2, mitochondrial (PANK2); PANK2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
47-570, Full length protein
Sequence
SLSLDGGTVNPPRVREPTGREAFGPSPASSDWLPARWRNGRGGRPRARLCSGWTAAEEARRNPTLGGLLGRQRLLLRMGGGRLGAPMERHGRASATSVSSAGEQAAGDPEGRRQEPLRRRASSASVPAVGASAEGTRRDRLGSYSGPTSVSRQRVESLRKKRPLFPWFGLDIGGTLVKLVYFEPKDITAEEEEEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLCGRKGNLHFIRFPTHDMPAFIQMGRDKNFSSLHTVFCATGGGAYKFEQDFLTIGDLQLCKLDELDCLIKGILYIDSVGFNGRSQCYYFENPADSEKCQKLPFDLKNPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFFGLCCLLTGCTTFEEALEMASRGDSTKVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKREAVSKEDLARATLITITNNIGSIARMCALNENINQVVFVGNFLRINTIAMRLLAYALDYWSKGQLKALFSEHEGYFGAVGALLELLKIP
Sequence Length
524
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for PANK2 recombinant protein
This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,582 Da
NCBI Official Full Name
pantothenate kinase 2, mitochondrial isoform 2
NCBI Official Synonym Full Names
pantothenate kinase 2
NCBI Official Symbol
PANK2
NCBI Official Synonym Symbols
HSS; HARP; PKAN; NBIA1; C20orf48
NCBI Protein Information
pantothenate kinase 2, mitochondrial
UniProt Protein Name
Pantothenate kinase 2, mitochondrial
UniProt Gene Name
PANK2
UniProt Synonym Gene Names
C20orf48; hPanK2
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Product Notes
The PANK2 pank2 (Catalog #AAA116958) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 47-570, Full length protein. The amino acid sequence is listed below: SLSLDGGTVN PPRVREPTGR EAFGPSPASS DWLPARWRNG RGGRPRARLC SGWTAAEEAR RNPTLGGLLG RQRLLLRMGG GRLGAPMERH GRASATSVSS AGEQAAGDPE GRRQEPLRRR ASSASVPAVG ASAEGTRRDR LGSYSGPTSV SRQRVESLRK KRPLFPWFGL DIGGTLVKLV YFEPKDITAE EEEEEVESLK SIRKYLTSNV AYGSTGIRDV HLELKDLTLC GRKGNLHFIR FPTHDMPAFI QMGRDKNFSS LHTVFCATGG GAYKFEQDFL TIGDLQLCKL DELDCLIKGI LYIDSVGFNG RSQCYYFENP ADSEKCQKLP FDLKNPYPLL LVNIGSGVSI LAVYSKDNYK RVTGTSLGGG TFFGLCCLLT GCTTFEEALE MASRGDSTKV DKLVRDIYGG DYERFGLPGW AVASSFGNMM SKEKREAVSK EDLARATLIT ITNNIGSIAR MCALNENINQ VVFVGNFLRI NTIAMRLLAY ALDYWSKGQL KALFSEHEGY FGAVGALLEL LKIP. It is sometimes possible for the material contained within the vial of "Pantothenate kinase 2, mitochondrial (PANK2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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