Application Data
(Immobilized recombinant Human PDGF-B at 2ug/mL (100uL/well) can bind recombinant Human PDGFRA, the EC50 of Human PDGFRA is 109 ng/mL.)
PDGFRa/CD140a Recombinant Protein | PDGFRA recombinant protein
Recombinant Human PDGFRa/CD140a Protein
Gene Names
PDGFRA; CD140A; PDGFR2; PDGFR-2
Purity
>97% by SDS-PAGE.
Synonyms
PDGFRa/CD140a; N/A; Recombinant Human PDGFRa/CD140a Protein; CD140A; GAS9; PDGFR-2; PDGFR2; RHEPDGFRA; PDGFRA recombinant protein
Purity/Purification
>97% by SDS-PAGE.
Form/Format
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
Source
HEK293 Cells
Species
Human
Endotoxin
< 0.1 EU/ug of the protein by LAL method.
Tags
C-hFc&His
Reconstitution
Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Tag
C-hFc&His
Bio-Activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant Human PDGF-B at 2 ug/mL (100 uL/well) can bind recombinant Human PDGFRA, the EC50 of Human PDGFRA is 109 ng/mL.
Preparation and Storage
Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Avoid repeated freeze/thaw cycles.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Avoid repeated freeze/thaw cycles.
Application Data
(Immobilized recombinant Human PDGF-B at 2ug/mL (100uL/well) can bind recombinant Human PDGFRA, the EC50 of Human PDGFRA is 109 ng/mL.)
Application Data
(Immobilized recombinant Human PDGF-B at 2ug/mL (100uL/well) can bind recombinant Human PDGFRA, the EC50 of Human PDGFRA is 109 ng/mL.)
SDS-PAGE
(Recombinant Human PDGFRa/CD140a Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 110-130 kDa.)
SDS-PAGE
(Recombinant Human PDGFRa/CD140a Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 110-130 kDa.)
Related Product Information for PDGFRA recombinant protein
Description: Recombinant Human PDGFRa/CD140a Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gln24-Glu524) of human PDGFRa/CD140a (Accession #NP_006197.1) fused with an Fc, 6xHis tag at the C-terminus.
Background: This protein is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Background: This protein is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Product Categories/Family for PDGFRA recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
platelet-derived growth factor receptor alpha isoform 1
NCBI Official Synonym Full Names
platelet derived growth factor receptor alpha
NCBI Official Symbol
PDGFRA
NCBI Official Synonym Symbols
CD140A; PDGFR2; PDGFR-2
NCBI Protein Information
platelet-derived growth factor receptor alpha
UniProt Protein Name
Platelet-derived growth factor receptor alpha
UniProt Gene Name
PDGFRA
UniProt Synonym Gene Names
PDGFR2; RHEPDGFRA; PDGF-R-alpha; PDGFR-alpha; PDGFR-2
UniProt Entry Name
PGFRA_HUMAN
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Product Notes
The PDGFRA pdgfra (Catalog #AAA281427) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PDGFRa/CD140a, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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