IHC (Immunohiostchemistry)
(Figure-2: Immunohistochemical analysis of ACE2 in human kidney tissue using ACE2 antibody at 2 ug/ml.)
anti-Human ACE2 Polyclonal Antibody | anti-ACE2 antibody
ACE2 Antibody
Gene Names
ACE2; ACEH
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity chromatography purified via peptide column.
Synonyms
ACE2, Antibody; ACE2 Antibody; ACEH antibody; DKFZp434A014 antibody; ACE2 antibody; metalloprotease MPROT15 antibody; angiotensin-converting enzyme homolog antibody; angiotensin I converting enzyme 2 antibody; ACE-related carboxypeptidase antibody; angiotensin-converting enzyme 2 antibody; anti-ACE2 antibody
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity chromatography purified via peptide column.
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
805
Applicable Applications for anti-ACE2 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Immunogen
This Antibody was raised against a synthetic peptide corresponding to amino acids near the N terminus of human ACE2.
Preparation and Storage
Stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Figure-2: Immunohistochemical analysis of ACE2 in human kidney tissue using ACE2 antibody at 2 ug/ml.)
IHC (Immunohiostchemistry)
(Figure-2: Immunohistochemical analysis of ACE2 in human kidney tissue using ACE2 antibody at 2 ug/ml.)
WB (Western Blot)
(Figure-1: Western blot analysis of ACE2. Anti- ACE2 antibody was used at 1 ug/ml on human kidney lysate.)
WB (Western Blot)
(Figure-1: Western blot analysis of ACE2. Anti- ACE2 antibody was used at 1 ug/ml on human kidney lysate.)
Related Product Information for anti-ACE2 antibody
Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
angiotensin-converting enzyme 2
NCBI Official Synonym Full Names
angiotensin I converting enzyme 2
NCBI Official Symbol
ACE2
NCBI Official Synonym Symbols
ACEH
NCBI Protein Information
angiotensin-converting enzyme 2
UniProt Protein Name
Angiotensin-converting enzyme 2
UniProt Gene Name
ACE2
UniProt Synonym Gene Names
ACEH
UniProt Entry Name
ACE2_HUMAN
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Product Notes
The ACE2 ace2 (Catalog #AAA78519) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The ACE2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ACE2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the ACE2 ace2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACE2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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