ICC (Immunocytochemistry)
(Immunocytochemistry staining of K562 cells using ADAM10 antibody at 2 ug/mL.)
Rabbit anti-Human ADAM10 Polyclonal Antibody | anti-ADAM10 antibody
ADAM10 Antibody
Gene Names
ADAM10; RAK; kuz; AD10; AD18; MADM; CD156c; HsT18717
Reactivity
Human
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Ion exchange chromatography purified
Synonyms
ADAM10, Antibody; ADAM10 Antibody; KUZ; anti-ADAM10 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Ion exchange chromatography purified
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
748
Applicable Applications for anti-ADAM10 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to amino acids 732 to 748 of human ADAM10. This sequence is identical to those of bovine and rat origins and differs from that of mouse ADAM10 by one amino acid (2,4).
Target Name
ADAM10
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry staining of K562 cells using ADAM10 antibody at 2 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry staining of K562 cells using ADAM10 antibody at 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of ADAM10 in Jurkat whole cell lysate with ADAM10 antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of ADAM10 in Jurkat whole cell lysate with ADAM10 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-ADAM10 antibody
Proinflammatory cytokine tumor necrosis factor-alpha (TNF-a) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-a, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-a, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
Product Categories/Family for anti-ADAM10 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,047 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 10
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 10
NCBI Official Symbol
ADAM10
NCBI Official Synonym Symbols
RAK; kuz; AD10; AD18; MADM; CD156c; HsT18717
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 10
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 10
UniProt Gene Name
ADAM10
UniProt Synonym Gene Names
KUZ; MADM; ADAM 10
UniProt Entry Name
ADA10_HUMAN
Similar Products
Product Notes
The ADAM10 adam10 (Catalog #AAA308211) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADAM10 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ADAM10 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ADAM10 adam10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADAM10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.