ICC (Immunocytochemistry)
(Immunocytochemistry of ADAP in K562 cells with ADAP antibody at 10 μg/mL.)
Rabbit anti-Human, Mouse ADAP Polyclonal Antibody | anti-FYB antibody
ADAP Antibody
Gene Names
FYB; ADAP; PRO0823; SLAP130; SLAP-130
Reactivity
Human, Mouse
Applications
Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
Purity
ADAP Antibody is affinity chromatography purified via peptide column.
Synonyms
ADAP, Antibody; ADAP Antibody; ADAP; PRO0823; SLAP-130; SLAP130; FYN-binding protein; Adhesion and degranulation promoting adaptor protein; FYN binding protein (FYB-120/130); anti-FYB antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
ADAP Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
829
Applicable Applications for anti-FYB antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
ADAP antibody was raised against a 20 amino acid synthetic peptide from near the carboxy terminus of human ADAP.
Buffer
ADAP Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ADAP antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of ADAP in K562 cells with ADAP antibody at 10 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of ADAP in K562 cells with ADAP antibody at 10 μg/mL.)
WB (Western Blot)
(Western blot analysis of ADAP in K562 cell lysate with ADAP antibody at (A) 0.5 and (B) 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of ADAP in K562 cell lysate with ADAP antibody at (A) 0.5 and (B) 1 μg/mL.)
Related Product Information for anti-FYB antibody
ADAP Antibody: The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-κB family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
91,651 Da
NCBI Official Full Name
FYN-binding protein isoform 1
NCBI Official Synonym Full Names
FYN binding protein
NCBI Official Symbol
FYB
NCBI Official Synonym Symbols
ADAP; PRO0823; SLAP130; SLAP-130
NCBI Protein Information
FYN-binding protein; p120/p130; FYB-120/130; FYN-T-binding protein; SLP-76-associated phosphoprotein; adhesion and degranulation-promoting adaptor protein
UniProt Protein Name
FYN-binding protein
UniProt Gene Name
FYB
UniProt Synonym Gene Names
SLAP130; ADAP; p120/p130
UniProt Entry Name
FYB_HUMAN
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Product Notes
The FYB fyb (Catalog #AAA39734) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADAP Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ADAP can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the FYB fyb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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