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product-image-AAA284478_IHC13.jpg IHC (Immunohiostchemistry) (Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ADK antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Rabbit anti-Human ADK Polyclonal Antibody | anti-ADK antibody

ADK Antibody (C-term)

Gene Names
ADK; AK
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ADK, Antibody; ADK Antibody (C-term); Adenosine kinase; AK; Adenosine 5'-phosphotransferase; ADK; anti-ADK antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ADK.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
322-352
Sequence Length
327
Applicable Applications for anti-ADK antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohiostchemistry)

(Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ADK antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

product-image-AAA284478_IHC13.jpg IHC (Immunohiostchemistry) (Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ADK antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

WB (Western Blot)

(Western blot analysis of anti-ADK Pab in mouse liver tissue lysate (35ug/lane). ADK(arrow) was detected using the purified Pab.)

product-image-AAA284478_WB15.jpg WB (Western Blot) (Western blot analysis of anti-ADK Pab in mouse liver tissue lysate (35ug/lane). ADK(arrow) was detected using the purified Pab.)
Related Product Information for anti-ADK antibody
Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.
Product Categories/Family for anti-ADK antibody
References
Szkotak, A.J., et al., J. Membr. Biol. 192(3):169-179 (2003). Singh, B., et al., DNA Cell Biol. 20(1):53-65 (2001). Van Rompay, A.R., et al., Eur. J. Biochem. 261(2):509-517 (1999). Mathews, I.I., et al., Biochemistry 37(45):15607-15620 (1998). McNally, T., et al., Biochem. Biophys. Res. Commun. 231(3):645-650 (1997).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
132
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40545
NCBI Official Full Name
adenosine kinase isoform a
NCBI Official Synonym Full Names
adenosine kinase
NCBI Official Symbol
ADK
NCBI Official Synonym Symbols
AK
NCBI Protein Information
adenosine kinase
UniProt Protein Name
Adenosine kinase
UniProt Gene Name
ADK
UniProt Synonym Gene Names
AK
UniProt Entry Name
ADK_HUMAN

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Product Notes

The ADK adk (Catalog #AAA284478) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 322-352. The ADK Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ADK can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ADK adk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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